运动防治糖尿病肾病的铁代谢调控研究进展  

Advances of Iron Metabolism in Prevention of Diabetic Nephropathy by Exercise

作　　者：胡银平[1] 刘玉倩[1] 

机构地区：[1]河北师范大学,河北石家庄050024

出　　处：《廊坊师范学院学报（自然科学版）》2015年第2期62-65,共4页Journal of Langfang Normal University(Natural Science Edition)

基　　金：河北省自然基金(C2013205026);河北省教育厅重点基金(ZD20131100);河北师范大学研究生基金(201402024)

摘　　要：糖尿病肾病是常见的糖尿病微血管并发症之一,铁超载是糖尿病肾病的发病原因之一。研究发现,在糖尿病肾病早期进行适度的运动干预,可有效地延缓或预防糖尿病肾病的发展及恶化,避免肾衰竭的出现。适度运动能够促进身体调控铁代谢平衡,促使铁的重新分布,提高各组织抗氧化能力,使机体产生有益的生理适应。文章阐述了铁超载导致糖尿病肾病的发病机制,运动在糖尿病肾病早期的作用以及运动对铁代谢调控的研究进展。Diabetic nephropathy is one of the most common complications of diabetes mellitus. In recent years, people began to focus on the role of iron in oxidative stress in patients with diabetic nephropathy. Researches showed that moder- ate exercise intervention in early diabetic nephropathy could effectively delay or prevent the development and worsening of diabetic nephropathy. The ability of body to regulate iron homeostasis was promoted by moderate exercise, and the iron redistribution was improved to increase the antioxidant capacity of organizations, which were beneficial physiological adap- tations to exercise. In this paper, we discussed the iron overload leaded to pathogenesis of diabetic nephropathy, the role of exercise in the progression of diabetic nephropathy and advances of iron metabolism in prevention of diabetic nephropa- thy by exercise.

关 键 词：铁 运动 糖尿病肾病 氧化应激 

分 类 号：G804.7[文化科学—运动人体科学]