脱落细胞学TCT制片与检验的质量管理  

Quality control of TCT production and examination in exfoliative cytology

作　　者：孙春霞[1] 付银娜 王明明[1] 李瑞琴[1] 

机构地区：[1]河南中医学院第三附属医院,河南郑州450000

出　　处：《中国伤残医学》2015年第10期28-29,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨脱落细胞学检查TCT制片检测全过程的质量控制方法。方法：采用薄层液基细胞学检测技术（ Thin－Cytologic Test TCT）对宫颈脱落细胞、胸水、腹水、各种穿刺液中的脱落细胞进行制片检查分析。结果：薄层液基细胞检测技术从根本上解决了常规脱落细胞制片丢失细胞率高、假阴性率高和涂片质量差等技术难题，使肿瘤细胞的阳性检出率达95％以上，同时为多种脱落细胞学标本的检测提供了可靠的检测方法。结论：薄层液基细胞学检测技术全过程的质量管理对提高脱落细胞的阳性检出率、结果的准确性判断、对肿瘤的早期发现早期治疗具有重要临床意义。Objective：To discuss the quality control methods for the entire process of the exfoliative cytology TCT slices exami-nation.Methods：Using thinprep cytologic test technology （ Thin-Cytologic Test TCT） to analyse the pathologic slice of cervical cytology, pleural effusion, ascites, various puncture exfoliated cells, etc.Results： TCT solves the technical problems fundamentally like the high cells losing rate of regular exfoliated cell production, high false negative detection rate, the poor quality of pathological section, etc.This made the positive detection rate of tumour cells more than 95%.Moreover, the TCT provided a reliable detection function for detecting the various specimens of exfoliative cytology.Conclusion：The quality control during the entire process of TCT technique should have the im-portant clinical significance in ralsing the positive detection rate of exfoliated cells, determining the accuracy of the results, and achieving the early discovery and early treatment of cancers.

关 键 词：薄层液基细胞检测 细胞学 质量控制 

分 类 号：R446[医药卫生—诊断学]