产 IMP-1型碳青霉烯酶非脱羧勒克菌的分离与鉴定  

Isolation and Identification of L. adecarboxylata Producing IMP-1 Metallo-beta-lactamase

作　　者：齐杰[1] 刘贵建[1] 潘健[1] 马玉芝[1] 张婷菊[1] 刘志远[1] 

机构地区：[1]中国中医科学院广安门医院检验科,北京100053

出　　处：《现代检验医学杂志》2015年第2期52-54,57,共4页Journal of Modern Laboratory Medicine

基　　金：中国中医科学院广安门医院国家中医临床研究示范基地科研专项暨所级科研基金课题,批准号2011S242.

摘　　要：目的：分析碳青霉烯耐药非脱羧勒克菌（L．adecarboxylata）的耐药基因型。方法Vitek II Compact 鉴定细菌及药敏试验，PCR 扩增碳青霉烯酶基因。结果该株非脱羧勒克菌产 IMP-1型碳青霉烯酶。结论非脱羧勒克菌临床分离株较少见，此为首次自非脱羧勒克菌检出 IMP-1型金属酶。Objective To investigate the phenotype and genotype in a carbapenem resistant L.adecarboxylata strain.Methods Microbial identification and drug susceptibility test was done with VITEK II Compact.Carbapenemases genes were detected by PCR methods.Results The strain of carbapenem resistant L.adecarboxylata produced IMP-1 carbapenemase.Conclusion L.adecarboxylata was found only rarely in the clinical isolates.This was the first Isolate of L.adecarboxylata producing IMP-1 metallo-beta-lactamase.

关 键 词：非脱羧勒克菌 碳青霉烯类 IMP-1 金属酶 

分 类 号：R378.2[医药卫生—病原生物学] R446.5[医药卫生—基础医学]