脑心动脉粥样硬化中医证型与易患因素多中心相关研究  

Multi-center Study of TCM Syndrome Type Related To Risk Factors of Cardio-cerebral Atherosclerosis

作　　者：王思尹[1] 张艳[2] 

机构地区：[1]辽宁中医药大学第一临床学院 [2]辽宁中医药大学附属医院心肺康复科,沈阳110032

出　　处：《实用中医内科杂志》2015年第3期3-6,共4页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[主要目的]分析脑心动脉粥样硬化中医证型与易患因素相关性。[资料来源]选取辽宁中医药大学附属第一医院、辽宁中医药大学附属第二医院、锦州市中医院、鞍山市中医院、丹东市中医院2012年3月至2013年12月脑心动脉粥样硬化门诊及住院患者,发放多因素调查表。[选择文献量及依据]1研究类型：问卷调查。2研究对象：1年龄40~80岁。2符合脑动脉粥样硬化及冠状动脉粥样硬化诊断标准。3辨证分型：痰瘀互结、肝肾阴虚、气虚血瘀、脾虚湿盛。4知情同意,签署知情同意书。排除冠状动脉粥样硬化性心脏病、脑动脉粥样硬化。发放问卷450份,回收425份,有效400份。[数据提炼规则及应用方法]观测证型分布、年龄、体重指数、血压、血脂。用EXCEL表建立数据库。无症状记为0,有症状记为1。采用SPSS13.0 for windows软件,计算相对频数。正态分布均数加减标准差（sx±）表示,组间比较完全随机分组均数单因素方差分析,方差不齐Dunnett检验。[数据综合得出结果与结论]证型频数：痰瘀互结〉肝肾阴虚〉气虚血瘀〉脾虚湿盛。各证型平均年龄无明显差异（P〉0.05）。平均体重指数痰瘀互结高于气虚血瘀（P〈0.05）;其余各证型均无明显差异（P〉0.05）。55.00%患者体重指数超正常范围。TC、TG气虚血瘀低于痰瘀互结（P〈0.05）、肝肾阴虚低于痰瘀互结（P〈0.05）、痰瘀互结高于脾虚湿盛（P〈0.05）,其余各证型无明显差异（P〉0.05）。脑心动脉粥样硬化与年龄、肥胖、高血压、高血脂密切相关（正相关）。[未来展望]需进一步扩大样本量,以期有新的突破和发展。[Main Object] Analyze TCM syndrome type and the risk factors of cardio-cerebral atherosclerosis. [Data Source] Choose cardio-cerebral atherosclerosis outpatient and inpatient in Affiliated Hospital of Liaoning University of TCM, the Second Affiliated Hospital of Liaoning University of TCM, Jinzhou Hospital of TCM, Anshan Hospital of TCM and Dandong Hospital of TCM from March 2012 to December 2013, sanding cardio-cerebral atherosclerosis multivariate survey. [Literature Selection and Criterion] ①The research type：questionnaire. ②The object of study.① Aged 40 to 80 years old. ② Consistent with cerebral atherosclerosis and coronary atherosclerosis diagnostic criteria.③TCM syndrome type： phlegm and blood stasis type, liver and kidney Yin deficiency type, Qi deficiency and blood stasis type, wet filled spleen deficiency type. ④ Informed consent： written informed consent.There are 450 questionnaires,returned 425 and 400 valid. [Data Extracting and Method] Observation TCM syndrome type distribution, age, BMI, blood pressure, blood lipids. Survey information is used EXCEL table entry, establishment of a database. Asymptomatic as 0, symptomatic as 1, symptoms statistics. Using SPSS13.0 for windows statistical software for processing of the frequency TCM syndrome type and statistically calculating relative frequency. Normally distributed data was represented as（x＋ s）. The groups were compared using completely randomized comparison with ANOVA, if the variance using Dunnett test. [Results and Conclusions] Frequency distribution of the TCM syndrome type in order： phlegm and blood stasis type〉liver and kidney Yin deficiency type〉Qi deficiency and blood stasis type〉wet filled spleen deficiency type. There was no significant difference （P〉0.05） in the average age of various syndrome. There were significant differences about average BMI in phlegm and blood stasis type and Qi deficiency and blood stasis type （P〈0.05）.The rest of the syndrome showed no significant difference （P〉0.05�

关 键 词：脑心动脉粥样硬化 胸痹 中医证型 易患因素 痰瘀互结 肝肾阴虚 气虚血瘀 脾虚湿盛 年龄 体重指数 血压 血脂 相关性 横断面调查 多中心研究 循证医学 系统综述 

分 类 号：R541.4[医药卫生—心血管疾病]