品行障碍青少年反馈相关负波特点的研究  

The Study of Feedback-related Negativity Responses in Adolescents with Conduct Disorder

作　　者：高一点 陈海燕[1] 贾惠侨[1] 蒋雅丽[1] 张积标[1] 姚树桥[1] 

机构地区：[1]中南大学湘雅二医院医学心理学研究所,长沙410011

出　　处：《中国临床心理学杂志》2015年第2期191-195,共5页Chinese Journal of Clinical Psychology

基　　金：国家科技支撑计划课题(2009BAI77B02)

摘　　要：目的：通过观察品行障碍（conduct disorder,CD）青少年反馈相关负波（Feedback-related negativity,FRN）波幅与潜伏期的变化,进一步探讨其反馈评价过程的特点。方法：对21名符合DSM-IV品行障碍诊断标准的13～17岁青少年和21名正常被试完成简单赌博任务时进行ERP检测。采用FRN的波幅和潜伏期作为指标,比较CD组与正常对照组青少年评价反馈结果过程的特点。结果：1CD组与对照组相比,FRN波幅差异具有统计学意义（P〈0.05）,CD组FRN波幅明显减小。2CD组与对照组相比,FRN潜伏期两组间比较差异无统计学意义（P〉0.05）。结论：与正常组相比,品行障碍青少年的FRN存在异常,这可能在品行障碍的发病机制与症状表现中起着重要作用。FRN波幅可能是品行障碍的属性指标。Objective： The current study was aimed at asking whether feedback-related negativity（FRN） would be ab-normal in adolescents with conduct disorder（CD）. Methods： We investigated brain responses to gain versus loss conditionsin feedback valuation with a single outcome gambling（SOG） task using event-related potentials（ERPs） in 21 conduct disor-der adolescents and 21 control subjects. Results： Main effect for valence（loss/gain） in amplitudes of FRN was salience ineach group, but not magnitude（10/50）. A broad FRN amplitude increase was evident for loss condition relative to win condi-tion in each group. Compared with control subjects, amplitudes of FRN were significantly more decreased in adolescentswith conduct disorder. Conclusion： We suggested that these findings reflect an impairment of feedback evaluation in ado-lescents with conduct disorder, which results in a propensity for behavioral disinhibition.

关 键 词：品行障碍 事件相关电位 反馈相关负波 

分 类 号：R395.1[哲学宗教—心理学]