Ncpap联合小剂量酚妥拉明治疗老年重症肺炎疗效观察  

Curative effect of Ncpap combined with small dose of phentolamine in treatment of elderly patients with severe pneumonia

作　　者：陈凯[1] 孙爱华 

机构地区：[1]浙江省绍兴市第六人民医院内科,浙江绍兴312000 [2]浙江省医学高等专科学校,浙江杭州310053

出　　处：《中国现代医生》2015年第11期29-31,共3页China Modern Doctor

基　　金：浙江省医药卫生一般研究计划A类(2011KYA005)

摘　　要：目的观察经鼻持续气道正压通气（Ncpap）联合小剂量酚妥拉明治疗老年重症肺炎的临床效果。方法选取2013年2月～2014年1月于我院诊治的重症肺炎老年患者共95例，随机原则分为对照组47例和观察组48例，对照组实施常规治疗联合Ncpap，观察组实施常规治疗联合Ncpap和小剂量酚妥拉明治疗。比较两组患者的各项临床症状改善时间、住院时间、血气指标变化、治疗总有效率。结果观察组各项临床症状（肺部哕音、气促、紫绀、肝脏回缩）消失时间和住院时间均显著短于对照组（P〈0．05）；治疗12h后，两组患者的各项血气指标（PaO2、PaCO2）均较治疗前改善明显（P〈0．05），且观察组血气指标改善优于对照组（P〈0．05）；观察组和对照组的治疗总有效率分别为95．8％和85．1％，观察组高于对照组（P〈0．05）。结论对临床重症肺炎的老年患者实施Ncpap联合小剂量酚妥拉明治疗，患者症状改善快，住院时间短，效果显著，值得推广。Objective To observe the clinical effect of nasal continuous positive airway pressure （Ncpap） combined wath small dose of phentolamine in treatment of elderly patients with severe pneumonia. Methods A total of 95 cases of elderly patients with severe pneumonia in our hospital from February 2013 to January 2014 were chosen. And they were randomly divided into the control group（47 cases） and the observation group（48 cases）. The control group received the routine therapy combined with Ncpap, while the observation group was given the conventional treatment combined with Ncpap and small dose phentolamine treatment. The clinical symptom improvement time, the hospitalization time, blood gas index changes, the total efficiency of treatment in two groups were compared. Results The clinical symptoms disap- peared time （pulmonary rales, shortness of breath, cyanosis, liver retraction） and hospital stay of the observation group were significantly shorter than those in control group （P〈0.05）; After treatment 12 h, the blood gas（PaO2, PaCO2） in patients of the two groups were improved significantly than before treatment （P〈0,05）; And observation group blood gas improved better than the control group （P〈0.05）; The total effective rate of the observation group and the control group was 95.8% and 85.1%, the total effective rate of observation group was higher than control group （P〈0.05）. Con- clusion Ncpap combined with small dose phentolamine are used in treatment of elderly patients with severe pneumonia, the symptoms of the patients are improved quickly, and with shorter hospital stay, the effect is significant, worthy of promotion.

关 键 词：NCPAP 酚妥拉明 小剂量 重症肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]