中西医结合治疗糖尿病临床疗效分析及不良反应观察  

Diabetes Clinical Efficacy Analysis and Adverse Reactions Observed in Combination Therapy

作　　者：俞文琴[1] 韩祖亮[1] 

机构地区：[1]杭州市萧山区第一人民医院,浙江杭州311200

出　　处：《中华中医药学刊》2015年第5期1232-1234,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨糖尿病患者应用中西医结合治疗临床疗效及其不良反应观察,为临床诊断治疗提供一定的参考价值。方法:本组82例糖尿病患者根据随机数字表法随机分为对照组和观察组各41例。对照组采用西药给予治疗,观察组在对照组基础上结合中药汤剂治疗。结果:观察组治疗后总有效率(92.68%)显著高于对照组(73.17%),且有统计学差异(P<0.05);观察组治疗后TC、TG、LDL变化显著低于治疗前及对照组治疗后,而HDL显著高于治疗前及对照组治疗后,且均有统计学差异(P<0.05);观察组治疗后FBG、2h PG及Hb A1c比较显著低于对照组治疗后,且有统计学差异(P<0.05);观察组治疗后血浆比黏度、纤维蛋白原及红细胞压积显著低于治疗前及对照组治疗后,且有统计学差异(P<0.05);观察组不良反应发生率显著低于对照组,且有统计学差异(P<0.05)。结论:糖尿病患者应用中西医结合治疗临床疗效显著,具有重要临床研究价值,值得进一步推广应用。Objective： To investigate the application of diabetic patients in combination therapy clinical efficacy and adverse reactions observed to provide certain reference value for clinical diagnosis and treatment. Methods ： 82 cases of di- abetic patients in this group were randomly divided into two groups according to the random number table （ n = 41 ） and observation group （n = 41 ）. The control group was given medicine treatment, observation group combined decoction treatment on the basis of the control group. Results： The total effective rate （92.68%） was significantly higher （73. 17% ） after treatment, and there is statistically significant （P 〈 O. 05 ） ; observation group after treatment TC, TG, LDL varies significantly lower than before treatment and in the control group, while HDL was significantly higher than the con- trol group before treatment and after treatment, and were statistically significant （P 〈 O. 05 ） ; observation group after treatment FBG, 2hPG and compare HbA1 c was significantly lower than in the control group, and there is statistically sig- nificant difference （ P 〈 O. 05 ） ; observation group after treatment plasma viscosity, fibrinogen and hematocrit were signifi- cantly lower than pre - treatment and post - treatment control group, and there is statistically significant （ P 〈 0.05 ） ; ad- verse reactions observed group the incidence was significantly lower than the control group, and there is statistically sig- nificant （P 〈 0.05 ）. Conclusion ： Patients with diabetes Integrative Medicine significant clinical effect has important clin- ical research value, worthy of further application.

关 键 词：糖尿病 中西医 临床疗效 不良反应 

分 类 号：R581.1[医药卫生—内分泌]