粉尘螨滴剂舌下含服治疗支气管哮喘的疗效观察  

Observation on the efficacy of sublingual immunotherapy of bronchial asthma with dust mite drops

作　　者：金艺凤[1] 方蕾[1] 汪向海[1] 邢敏[1] 

机构地区：[1]皖南医学院附属弋矶山医院呼吸内科,安徽芜湖241001

出　　处：《皖南医学院学报》2015年第2期171-173,共3页Journal of Wannan Medical College

摘　　要：目的:评估粉尘螨滴剂治疗支气管哮喘的疗效。方法:选择我科粉尘螨过敏的支气管哮喘患者207例,随机分为两组,治疗组(100例):粉尘螨滴剂舌下滴服联合沙美特罗氟替卡松吸入治疗;对照组(107例):采用沙美特罗氟替卡松吸入治疗。评价疗效指标包括哮喘症状评分、哮喘控制测试、肺功能。结果:治疗组患者的哮喘症状评分、哮喘控制测试、肺功能指标与对照组相比明显改善(P<0.05)。结论:粉尘螨滴剂治疗支气管哮喘有效、安全,值得临床推广使用。Objective：To observe the curative effects of sublingnal administration of dust mite drops on bronchial asthma. Methods ：207 adult patients of bronchial asthma allergic to dust mites were included and assigned randomly to treatment group（ n = 100 ,treated with sublingual dust mite drops plus inha- lation of salmeterol/flutieasone propionate） and control group （n = 107, managed with simple inhalation of salmeterol/flutieasone propionate）. The indica- tots,including asthma symptoms scores, asthma control test and pulmonary function, were evaluated for the two groups. Results： The patients in the treat- ment group were improved a lot regarding the asthma symptoms scores, asthma control test and lung function （P 〈 0. 05 ）. Conclusion：Sublingual adminis- tration of dust mite drops can be efficacious and safe for bronchial asthma, and is worthy of wider clinical recommendation.

关 键 词：支气管哮喘 粉尘螨 沙美特罗氟替卡松 疗效 

分 类 号：R562.25[医药卫生—呼吸系统]