桃仁膝康颗粒水提取及纯化工艺优选  

Optimization of Water Extraction and Purification Processes of Taoren Xikang Granules

作　　者：杜天信[1,2] 张磊[2] 杜志谦[1,2] 夏华玲 王莉萍[2] 

机构地区：[1]河南省正骨研究院,河南洛阳471002 [2]河南中医学院,河南郑州450046

出　　处：《中医学报》2015年第4期568-570,共3页Acta Chinese Medicine

摘　　要：目的:优选桃仁膝康颗粒的水提取及纯化工艺。方法:以芍药苷和干浸膏收率为指标,采用正交试验法,考察提取次数、提取时间和加水量对提取工艺的影响;采用水提醇沉法对提取液进行纯化,以芍药苷和干浸膏收率为指标,对乙醇体积分数进行考察。结果:最佳提取工艺为加8倍量水,提取2次,每次1.5 h;乙醇体积分数为70%。结论:优选的工艺合理可行,可为工业生产提供参考。Objective：To optimize the water extraction and purification processes of Taoren Xikang granules. Method：The paeoniflorin and dry extract rate are indexes, using orthogonal test,inspecting the purification processes affection by the additive quantity of water of extract time and number of times, purification of the extracting solution by water extract-alcohol precipitation, the paeoniflorin and dry extract rate are indexes, inspecting the ethanol concentration. Results ： Optimum extraction process was as follows ： extracted 2 times with 8 times the amount of water, 1.5 hours each time;the consistency of ethanol is 70%. Conclusion：The optimized process is reasonable and feasible, and it can provide reference for the industrialized production.

关 键 词：桃仁膝康颗粒 芍药苷 正交试验 水提取工艺 纯化工艺 

分 类 号：R284.2[医药卫生—中药学]