胰岛素样生长因子1及其在组织和器官生长发育中的作用  

Insulin-like Growth Factor 1 and its Roles in the Development of Tissues and Organs

作　　者：曾永芬[1] 黄义德[1] 

机构地区：[1]福建师范大学生命科学学院,中国福建福州350108

出　　处：《生命科学研究》2015年第2期165-168,184,共5页Life Science Research

基　　金：福建省教育厅重点项目(JA12061)

摘　　要：胰岛素样生长因子1(IGF1),具有调节组织细胞增殖、分化、有丝分裂等功能。研究表明IGF1不仅参与众多疾病的发生,还参与了不同组织和器官的发育过程。对IGF1信号通路及其在机体发育中的作用进行了综述。Insulin-like growth factor 1 （IGF1） is a multi-functional protein which plays the important roles in regulating cell proliferation, differentiation and mitosis. Studies have shown that IGF1 is not only involved in the occurrence of many diseases, but also participated in the development process of different tissues and organs. The IGF1 signaling pathway and its roles in the development of tissues and organs are reviewed.

关 键 词：胰岛素样生长因子1 胰岛素样生长因子1受体 胰岛素样生长因子结合蛋白 信号通路 发育 

分 类 号：Q71[生物学—分子生物学]