针刺作用于脑卒中后NSCs增殖的多信号通路研究进展  

Research Progress of Proliferous Multiple Signaling Pathways by NSCs Induced by Acupunture After Stroke

作　　者：麻聪聪[1] 樊小农[1] 王晓光[2] 樊同涛[2] 常女子 

机构地区：[1]天津中医药大学第一附属医院,天津300193 [2]天津中医药大学,天津300193

出　　处：《河南中医》2015年第4期741-744,共4页Henan Traditional Chinese Medicine

基　　金：天津市高等学校科技发展基金计划项目(编号:20090206);天津市应用基础与前沿技术研究计划资助项目(编号:10JCBJC12700)

摘　　要：针刺不仅在整体水平上促进神经细胞的代偿性修复,减轻神经功能缺损程度,还可以作用到各个神经通路进行调节。针刺可以抑制或者上调很多蛋白的表达,进而影响各个信号通路。有些针刺效应更能作用于各个信号通路相链接的靶点蛋白上,从整体上抑制负性的信号通路,促进正性的信号通路。但目前针刺对各信号通路的调控主次作用不明确,各信号通路发挥的主次作用也不明确,仍需进一步研究,以寻求更明确的作用机制和作用靶点,明确主次关系。Acupuncture can not only generally promote the compensatory repair of the nerve cells, but also act on various neural pathways to perform regulation. Acupuncture can inhibit or promote the expression of many proteins, and thus influence various signal pathways. Acupuncture sometimes can impact he targets of rapamycin which connect various signal pathways to inhibit neg- ative signal pathway and enhance positive signal pathways on the whole. However,the primary, and secondary roles of the regula- tion performed on the signal pathways by current acupuncture are not definite, so are the regulation roles of signal pathways. Therefore ,further study should be conducted to seek for more exact action mechanism and targets to make clear the primary and secondary roles.

关 键 词：针刺 脑卒中 NSCS 信号通路 

分 类 号：R255.2[医药卫生—中医内科学]