持续气道正压通气在OSAHS合并缺血性心脏病患者中的生活质量研究  

Study of CPAP on quality of life in OSAHS patients complicated by ischemic heart disease

作　　者：杨娟[1] 盛凯华[1] 龚海燕[1] 周燕燕[2] 施亚娟[3] 

机构地区：[1]江苏省启东市人民医院呼吸内科,启东226200 [2]江苏省启东市人民医院心内科,启东226200 [3]江苏省启东市人民医院心电图室,启东226200

出　　处：《南通大学学报（医学版）》2015年第2期122-125,共4页Journal of Nantong University(Medical sciences)

基　　金：南通市社会发展资助项目(HS12930)

摘　　要：目的:探讨SF-36量表应用于阻塞型睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)合并缺血性心脏病(ischemic heart disease,IHD)患者,进行生命质量评分,观察无创性持续气道正压通气(continuous positive airway pressure,CPAP)在其治疗中的临床价值。方法:将71例确诊为OSAHS合并IHD的患者随机分为两组:联合治疗组(A组)和基础治疗组(B组)。A组在传统的内科治疗基础上加用整夜(每晚>7 h)的CPAP治疗,B组仅采用传统的内科治疗手段。在治疗前和治疗1年后,应用中文版SF-36量表进行生命质量评价。统计方法采用t检验、方差分析、秩和检验等,使用SPSS 18.0处理数据。结果:A、B两组患者的年龄构成比、体质量指数(body mass index,BMI)及治疗前SF-36量表8个维度的评分差异均无统计学意义(均P>0.05)。A组治疗后基于SF-36量表8个维度分数、躯体健康得分、心理健康得分、总得分均较治疗前有显著改善(P<0.01)。B组治疗前、后除精神健康方面差异无统计学意义外,其余差异有统计学意义(P<0.01)。A组治疗前后躯体健康得分、心理健康得分、总得分变化率分别为67.66%(74.22%)、26.67%(51.01%)、44.62%(51.57%),与B组的2.71%(13.22%)、5.00%(9.71%)、3.34%(10.21%)比较差异均有统计学意义(P<0.01)。结论:在内科药物治疗基础上采用无创性CPAP治疗OSAHS合并IHD,能够提高患者的生活质量,为今后在临床工作中进一步加强CPAP治疗提供科学依据,值得临床推广应用。Objective： To measure health-related quality of life score with patients of obstructive sleep apnea-hypopnea syndrome（OSAHS） associated with ischemic heart disease（IHD）, and to estimate the clinical value of noninvasive continuous positive airway pressure（CPAP） ventilation by SF-36 survey. Methods：71 cases of OSAHS associated with IHD were randomly divided into two groups： group A is the combined treatment group, group B is the basic treatment group. Group A got a basic medical treatment combined with overall night CPAP treatment（every night〉7 hours）, and group B only got a basic medical treatment. Health-related quality of life measurements were taken by SF-36 survey before treatments and post-one-year treatment. The test, analysis of variance, rank sum test. were taken as statistical methods by data processing software SPSS 18.0. Results：There were no significant differences in age composition ratio and body mass index（BMI） between two groups（P〉0.05）. Eight dimensions of SF-36 survey there was no significant differences（P〉0.05） between two groups before treatment. Eight dimensions of SF-36 survey of group A between before treatment and post-one-year treatment were significant differences, which physical health score, mental health score and the total score were significantly improved （P〈0.01）. Between before treatment and post-one-year treatment of group B seven dimensions of SF-36 survey, physical health score, mental health score and the total score were significantly differences（P〈0.01）, except mental health score. The group A between before treatment and post-treatment, the improvement rate of physical health score, mental health score and the total score respectively was 67 . 66%（ 74 . 22%） , 26 . 67%（ 51 . 01%） , and 44 . 62%（ 51 . 57%） , and those of group B respectively was 2.71%（13.22%）, 5.00%（9.71%） , 3.34%（10.21%）, three indicators of both groups were statistically significant differences（P〈0.01）. Conclusion： A basi

关 键 词：阻塞型睡眠呼吸暂停低通气综合征 缺血性心脏病 持续气道正压通气 SF-36量表 生活质量 

分 类 号：R563.8[医药卫生—呼吸系统]