木村病45例临床分析  

Clinical analysis of 45 cases with Kimura disease

作　　者：刘立梅[1] 高清平[1] 王则胜[1] 王琼玉[1] 

机构地区：[1]武汉大学人民医院,武汉430060

出　　处：《内科急危重症杂志》2015年第2期101-104,共4页Journal of Critical Care In Internal Medicine

摘　　要：目的:探讨木村病的临床表现、诊断及治疗特点。方法:回顾性分析45例木村病的临床资料。结果:45例均以局部包块为主要表现,23例累及头面部,11例累及颈部,此外,还有腹股沟3例,胸壁3例,腹壁3例,髂前上棘1例,锁骨1例;16例血常规示嗜酸性粒细胞比例增高,其中嗜酸性粒细胞绝对值增高的有13例;3例检测了血清Ig E,2例显著升高。多使用手术切除或糖皮质激素治疗。结论:木村病是少见病,诊断主要依据临床表现、血常规、免疫球蛋白检测、病理检查等,手术切除或激素治疗后联合小剂量的放疗可有效预防复发。Objective： To explore the clinical characteristics, diagnosis and the therapeutic effect of Kimura disease. Methods： Clinical data of 45 patients with Kimura disease were analyzed retrospectively. Results：All the patients presented with local masses, 23 cases involved head and face, 11 cases in neck region. The other involved regions were inguinal region （3 cases）, chest wall （3 cases）, abdominal wall （3 cases）, anterior superior iliac spine （1 case） and clavicle（ 1 case）. 16 cases showed increased proportion of eoslnophil, of which 13 cases had raised absolute eosinophil count. The serum level of IgE was measured in 3 cases, of which 2 cases increased remarkablely. Most patients received surgical excision or horm- onotherapy. Conclusions： Kimura disease is a rare disease. The diagnosis based on clinical manifestation, blood routine test, immunoglobulin detecting, pathological examination and so on. Low dose of radiotherapy is necessary for preventing relapse after operation and hormonotherapy.

关 键 词：木村病 淋巴肉芽肿 嗜酸性粒细胞增多 IgE增高 

分 类 号：R593.9[医药卫生—内科学]