过敏性紫癜儿童检测特异性IgE水平的临床意义分析  

Analysis of clinical significance of specific Ig E level detection in anaphylactoid purpura children

作　　者：钟乐璇[1] 唐普润[1] 彭云[1] 

机构地区：[1]广州医科大学附属第二医院儿科,510260

出　　处：《中国实用医药》2015年第12期49-50,共2页China Practical Medicine

摘　　要：目的分析探究过敏性紫癜儿童检测特异性免疫球蛋白E(Ig E)水平的临床意义。方法 86例过敏性紫癜患儿入院后均于清晨采集空腹静脉血3 ml,采用由瑞典Parmacia公司变应原体外检测系统的酶联免疫捕获法进行特异性Ig E定量检测,特异性Ig E≥0.35 k UA/L为阳性,计数患儿各类过敏原引起血清特异性Ig E水平升高的阳性率。结果据统计40例患儿血清特异性Ig E水平高于正常值,即特异性Ig E阳性率达46.51%。户尘螨、粉尘螨、热带螨、屋尘总阳性率为55.00%,牛奶、鸡蛋的阳性率比较高,鳕鱼、黄豆、小麦、蟑螂少许阳性,猫毛皮、狗毛皮未发现阳性。结论绝大部分过敏性紫癜患儿体内的特异性Ig E水平均会出现不同程度的增高,超过正常水平的血清特异性Ig E水平,对于诊断患儿过敏原造成的过敏性紫癜的诊断具有一定的指导意义,因此,控制患儿与以上变应原接触是防治过敏性紫癜的关键。Objective To analyze and investigate the clinical significance of specific immunoglobulin E （IgE） level detection in anaphylactoid purpura children. Methods A total of 86 children with anaphylactoid purpura were taken 3 ml fasting venous blood after administration. Their specific IgE levels were detected by enzyme-linked immune capture method by allergens in vitro test system from Parmacia Company in Sweden. Positive was determined as specific IgE ≥0.35 kUA/L. Positive rates of increased levels of specific IgE by various allergens were counted.Results There were 40 children with higher serum specific IgE level as 46.51% than standard value. The total positive rate was 55.00% of dermatophagoides pteronyssinus, dermatophagoides farina, tropical mite, and house dust. Milk and egg had high positive rate, and gadus, soybean, wheat, and cockroach had few positive rate, while there was no positive rate in fur of cat and dog.Conclusion Most children with anaphylactoid purpura have increased levels of specific IgE, and its level provides certain guide significance for diagnosis allergen of anaphylactoid purpura. Therefore, it is key for prevention anaphylactoid purpura to avoid contact of children from those mentioned allergens.

关 键 词：过敏性紫癜 儿童 

分 类 号：R725.5[医药卫生—儿科]