临床药师干预前后经皮介入封堵术围术期抗菌药物应用分析  

Application Analysis of Antibiotics in the Perioperative Period of Percutaneous Transcatheter Closure before and after Intervention by Clinical Pharmacists

作　　者：孙飞龙[1] 史国兵[1] 赵庆春[1] 任天舒[1] 李泽[1] 

机构地区：[1]沈阳军区总医院药剂科,沈阳110840

出　　处：《中国药房》2015年第14期1990-1992,共3页China Pharmacy

摘　　要：目的:探讨临床药师参与经皮介入封堵术(TC)围术期预防用药管理对提高TC用药合格率的作用。方法:随机抽取2011年6月-2012年5月(干预前)、2012年6月-2013年5月(干预后)我院先心内科住院行TC患者病历各75例,对干预前后TC围术期药物选择、给药时机、持续用药时间、分级管理合格率等方面的合理性进行比较。结果:经过干预,TC围术期抗菌药物选择合格率从66.4%提高至98.7%,给药时机合格率从76.7%提高至98.1%,持续用药时间合格率由22.9%提高至98.9%,分级管理合格率由92.3%提高至100%,总DDDs明显下降,与干预前比较差异均有统计学意义(P<0.01或P<0.05)。结论:临床药师参与用药管理,对提高TC围术期用药合格率起到了积极的推动作用。OBJECTIVE： To explore the effects of clinical pharmacists participating in perioperative prophylaxis management of percutaneous transcatheter closure （TC） on the improvement of qualified rate of TC medication. METHODS： The records of inpatients with TC in the cardiology department of our hospital from Jun. 2011 to May 2012 （before intervention） and Jun. 2012 to May 2013 （after intervention） were randomly collected, 75 cases for each. The rationalities in the TC perioperative were compared before and af- ter intervention, including the qualified rate of drug selection, duration time, continued treatment time and graded management, etc. RESULTS： After intervention, the qualified rate of antibiotics selection in the TC perioperative was increased from 66.4% to 98.7 %, the qualified rate of duration time was increased from 76.7 % to 98.1%, the qualified rate of continued treatment time was increased from 22.9% to 98.9% and the qualified rate of graded management was increased from 92.3% to 100%. The total DDDs was signifi- cantly decreased, compared with before intervention, there was significant difference （P〈0.01 or P〈0.05）. CONCLUSIONS： Clini- cal pharmacists participating in the medication management plays a positive role in the improvement of the qualified rate of TC perioper- ative period medication.

关 键 词：经皮介入封堵术 围术期 抗菌药物 临床药师 干预 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]