肠道菌群与2型糖尿病研究进展  

Research progress of the relationship between intestinal flora and type 2 diabetes mellitus

作　　者：李文婷[1] 潘道延 陈远程[1] 李章芳[1] 沈洁[1] 

机构地区：[1]南方医科大学第三附属医院内分泌代谢科,广州510630

出　　处：《中华临床营养杂志》2015年第2期121-124,共4页Chinese Journal of Clinical Nutrition

基　　金：广东省自然科学基金（S2013010016045）

摘　　要：2型糖尿病是一种代谢疾病，其发病率日益增加，造成了巨大的社会经济负担。肠道菌群指定居于人体肠道的微生物群体，作为与人类紧密联系的环境因素，参与人体生长发育、生理过程，甚至疾病状态。近年来关于肠道菌群与2型糖尿病的关系的研究已经成为内分泌代谢领域的热点问题。本文拟就2型糖尿病与肠道菌群的关系做一综述，梳理该方面研究的最新进展，提示这一领域的进一步研究方向。Type 2 diabetes is a metabolic disease with increasing prevalence, which causes great soci- oeconomic burden. Intestinal flora is the microbiota located in the human intestines, which are participating in human growth and development, physiological procedures, or even pathogenesis as a closely connected environ- mental factor. There have recently been rapid progresses in the research on the relationship between intestinal flora and type 2 diabetes in the field of endocrinology and metabolism. In this article, we reviewed the overall framework and research progress in the relationship between intestinal flora and type 2 diabetes, aiming to shed some light on the future research about this topic.

关 键 词：肠道菌群 2型糖尿病 胰岛素抵抗 肠道 代谢异常 

分 类 号：R587.1[医药卫生—内分泌]