彩色多普勒超声检测糖尿病患者滑车上动脉及球后动脉的血流动力学改变  

Detection on hemodynamics of supratrochlear artery and retrobulbar arteries by using color doppler flow imaging(CDFI) in diabetic patients

作　　者：高鑫 杨华[2] 马琳[2] 阚艳敏[2] 张树华[2] 李晓松[2] 

机构地区：[1]河北省唐山市开滦集团公司总医院超声科,063000 [2]河北联合大学附属医院超声科,河北省唐山市063000

出　　处：《中华全科医学》2015年第6期949-950,955,共3页Chinese Journal of General Practice

摘　　要：目的探讨糖尿病视网膜病变(diabetic retinopathy,DR)患者滑车上动脉(STCA)、球后动脉血流动力学变化及影响DR发生、发展的因素。方法选择住院确诊为2型糖尿病的患者112例,并根据各项眼底检查结果将其分为无糖尿病视网膜病变组(NDR组)52例和糖尿病视网膜病变组(DR组)60例,同期选择门诊健康体检者42例为正常对照组。测量上述研究对象的各超声参数,包括:眼动脉(OA)、视网膜中央动脉(CRA)及滑车上动脉(STCA)的收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)及血流阻力指数(RI)。结果 STCA与OA及CRA三条动脉间的血流参数均存在明显的正相关关系(r=0.75,P=0.001;r=0.897,P=0.001)。DR组、NDR组的滑车上动脉(STCA)、眼动脉(OA)、视网膜中央动脉(CRA)与对照组比较PSV、EDV下降,RI值增高(P<0.05)。非条件Logistic回归结果显示糖尿病病程、血糖水平是DR的独立危险因素。结论 STCA能够反映OA、CRA血流动力学改变,糖尿病病程及血糖水平是影响糖尿病患者视网膜病变发生、发展的独立危险因素。Objective To detect the hemodynamic changes of supratrochlear artery（STCA） and retrobulbar arteries of the diabetic patients by using Color Doppler Flow Imaging（CDFI） and explore possible implications and development factors of diabetic retinopathy （DR）. Methods One-hundred twelve patients with type 2 in cases group, all diabetic patients were divided into non-diabetic retinopathy group（ NDR ,56 cases） and diabetic retinopathy group（ DR,60 cases） accord- ing to the fundus examination results. 42 cases were in the control group. The peak systolic velocity（PSV） ,the end-dias- tolic velocity（EDV） and the resistive index（RI） of ophthalmic artery（OA） ,central retinal artery（CRA） and supratroch- lear artery（STCA） were measured using IU-22 ultrasonic equipment. Results There was good correlation between su- pratrochlear artery （STCA） and the ophthalmic artery （ OA）, central retinal artery （ CRA, r = 0.75, P= 0. 001 ; r = 0. 897, P = 0. 001 ,respectively）. PSV and EDV of supratrochlear artery（ STCA）, ophthalmic artery （OA） and central retinal ar- tery （CRA） in DR group and NDR group was decreased and RI increased much than those of control group. Conclusion Supratrochlear artery（STCA） can reflect the hemodynamic changes of ophthalmic artery （OA）, central retinal artery （CRA）. The course of history and blood glucose were the independent risk factors for the development of DR.

关 键 词：糖尿病视网膜病变 滑车上动脉 眼动脉 视网膜中央动脉 彩色多普勒血流显像 

分 类 号：R587.2[医药卫生—内分泌] R445.1[医药卫生—内科学]