不同腹膜透析治疗模式对透析患者钙磷代谢及PTH的影响  

The effect of different modes of peritoneal dialysis treatment to the hemodialysis patients calcium phosphorus metabolism and PTH

作　　者：娜孜亚·斯加克 岳华[1] 

机构地区：[1]新疆维吾尔自治区人民医院,新疆乌鲁木齐830002

出　　处：《国际泌尿系统杂志》2015年第3期403-406,共4页International Journal of Urology and Nephrology

摘　　要：目的比较采用日问非卧床腹膜透析（DAPD）与经典持续非卧床腹膜透析（CAPD）对钙磷代谢及盯H的影响。方法从新疆维吾尔自治区人民医院肾病科160例行腹膜透析患者中选取符合条件的83例，年龄在20～80岁，平均年龄为（45．26±16．14）岁，根据不同透析方式分为两组：CAPD组：共54例，男33例，女21例；DAPD组：共29例，男16例，女13例。CAPD组每次的透析剂量为6～8L、3～4次交换、夜间留腹（留腹的透析液浓度为1．5％）；DAPD组日间采用6～8L的透析剂量，每袋透析液交换时间为3—4h，夜间干腹。观察这些患者相关临床指标包括患者的一般资料、血钙（Ca^2＋）、血磷（P^3-）、甲状旁腺激素（PTH）以及残余肾功能。结果两组在一般资料比较中差异无统计学意义（P〉0．05），两组在血钙（Ca^2＋）、血磷（P^3-）、甲状旁腺激素（PTH）等方面差异均有统计学意义（P〈0．05），比较两组的超滤量以及比较透前残余肾功能与透后一年后残余肾功能差异均有统计学意义（P〈0．05）。结论行DAPD治疗的患者比经典的CAPD患者能更有效的控制钙磷代谢，并能更好的保护残余肾功能。Objectives To compare the effect of daytime ambulatory peritoneal dialysis（DAPD） and clas- sical continuous ambulatory peritoneal dialysis（CAPD） on calcium phosphorus metabolism and PTH. Methods Selected 83 cases of qualified patients from the 160 patients who got peritoneal dialysis in nephrology of Xinjiang Au- tonomous Region People＇s Hospital, age from 20 ~ 80, the average age was （45.26 ± 16.14）, divided them into two groups according to the different method of dialysis ： CADP group ： 54 cases, 33 men, 21 women ; DAPD group ： 29 cases, 16 men, 13 women. Dialysis dose of the CAPD group was 6 -8L, exchange for 3 ~ 4 times, abdomen left at night（the abdomen left concentration of dialysate was 1.5 % ） ;DAPD group used 6 ~ 8 L dialysis dose at day time, each bag of dialysate exchange time was 3 ~ 4h, dry abdomen at night. Observed these patients＂ related clinical indicators including the patient ＂s general information, blood calcium （ Ca^2＋ ）, blood phosphorus （ P3 ）, parathyroid hormone （PTH） and residual renal function. Experimental data expressed as X ± S, the comparison between the two groups u- sing t test and X2 test, P 〈 0.05 reflected the difference was statistically significant. Results The two groups＂ general data comparison had no statistical significance（ P 〉 0.05 ）. The differences in the two groups＇blood calcium （ Ca^2 ＋ ）, blood phosphorus（ P3 ） and parathyroid hormone （ PTH ） and so on were statistically significant （ P 〈 0. 05 ）, the comparison of two groups＇uhrafihration volume and comparison of residual kidney function before and a year after dialysate residual renal function differences were statistically signinifcant （ P 〈 O. 05 ）. Conclusions Pa- tients treated by DAPD can be more effective than classical CAPD patients in the calcium phosphorus metabolism control, and can better protect the residual renal function.

关 键 词：腹膜透析 钙 磷 

分 类 号：R459.51[医药卫生—治疗学]