无创机械通气治疗慢性肺源性心脏病合并Ⅱ型呼吸衰竭的临床疗效  

Clinical efficacy of noninvasive mechanical ventilation on chronic pulmonary heart disease combined with type II respiratory failure

作　　者：周松林[1] 徐文波[2] 

机构地区：[1]江西省胸科医院心血管内科,江西南昌330006 [2]深圳市坪山新区人民医院功能科,广东深圳518118

出　　处：《中国现代医学杂志》2015年第12期106-109,共4页China Journal of Modern Medicine

摘　　要：目的分析无创机械通气治疗慢性肺源性心脏病合并Ⅱ型呼吸衰竭的临床疗效。方法选择在江西省胸科医院接受住院治疗的慢性肺源性心脏病合并Ⅱ型呼吸衰竭患者作为研究对象,随机分为接受常规治疗的对照组及接受无创机械通气治疗的观察组。比较两组患者的血气水平、呼吸及心率水平、炎症因子水平等差异。结果观察组患者接受无创机械通气治疗后的PH、Pa O2、Sa O2水平明显高于对照组患者;Pa CO2水平低于对照组患者(P<0.05);观察组患者接受治疗后的呼吸及心跳频率均大幅低于对照组患者(P<0.05);观察组患者接受治疗后的IL-8、TNF-α、Neu/Leu值均明显低于对照组患者(P<0.05)。结论无创机械通气治疗可以明显改善慢性肺源性心脏病合并Ⅱ型呼吸衰竭患者的血气水平及呼吸状态,降低炎症因子水平。[Objective]To analyze clinical efficacy of noninvasive mechanical ventilation（NIMV） on chronic pulmonary heart disease（CPHD） combined with type II respiratory failure. [Methods]One hundred and two cases of patients with CPHD combined type II respiratory failure as research subjects were randomly divided into control group with conventional treatment and observation group with NIMV therapy. The blood gas levels, breathing and heart rates and inflammatory factor levels in both groups were compared. [Results]The PH, Pa O2, Sa O2 levels in the observation group were obviously higher than those in the control group, while the Pa CO2 level in the observation group was lower（P〈0.05）. The breathing and heart rates in the observation group were significantly lower than those in the control group（P〈0.05）. The IL-8, TNF-αand Neu/Leu values in the observation group were significantly lower than those in the control group（P〈0.05）.[Conclusions]Noninvasive mechanical ventilation treatment can significantly improve blood gas levels and respiratory condition in patients with CPHD combined with type II respiratory failure, decrease levels of inflammatory cytokines.

关 键 词：慢性肺源性心脏病 呼吸衰竭 无创机械通气 

分 类 号：R541.5[医药卫生—心血管疾病]