肠道恶性肿瘤超声造影增强模式及其定量参数特征初探  

Primary study on characteristics of enhancement pattern and quantitative parameters of contrast-enhanced ultrasound of intestinal malignant tumors

作　　者：孙成瑜 陈烨[1] 姚炜[1] 李延芳[1] 程文漪[1] 王颖[1] 雷凯荣[1] 

机构地区：[1]同济大学附属杨浦医院超声医学科,上海200090

出　　处：《肿瘤影像学》2015年第1期52-54,58,共4页Oncoradiology

摘　　要：目的:分析肠道恶性肿瘤的超声造影(CEUS)增强模式及时间-强度曲线特点,初步探讨CEUS诊断肠道恶性肿瘤的价值。方法:对26例肠道恶性肿瘤患者行CEUS检查,观察病灶的增强模式,利用时间-强度曲线获取肿瘤组织及瘤旁肠壁的定量参数。结果:CEUS显示26例患者肠道恶性肿瘤的增强模式均为不均匀性增强,7例病灶局部可见造影剂无充填区。以高增强为主,23例(88.5%)病灶表现为高增强,17例(65.4%)由病灶周围开始向心性增强;以快速消退为主,22例(84.6%)显示造影强度持续时间较短,较早消退。肿瘤组织与瘤旁肠壁的起始-达峰时间(ATP)和绝对增强强度差异有统计学意义(P<0.05)。结论:肠道恶性肿瘤具有特征性的CEUS表现,通过时间-强度曲线可动态观察肠道恶性肿瘤的血流灌注情况,CEUS对肠道恶性肿瘤的诊治具有一定的临床应用价值。Objective： To analyze the characteristics of enhancement pattern and time-intensity curve of contrast-enhanced ultrasound （CEUS） of intestinal malignant tumors, and to evaluate the diagnostic value of CEUS in intestinal malignant tumors. Methods： A total of 26 patients with intestinal malignant tumors undertook CEUS examination. The enhancement patterns were observed. The quantitative parameters of tumor tissues and peritumoral intestinal wall were acquired by time-intensity curve. Results：CEUS showed that all the patients had heterogeneous enhancement pattern, and 7 patients with empty contrast areas in the lesions. The lesions mainly showed high enhancement pattern, 23 patients （88.5%） with high enhancement and 17 patients （65.4%） with centripetal enhancement. The lesions also mainly showed fast washout, 22 patients （84.6%） with high enhancement maintaining for a short period of time and washed out quite early. There were signiifcant differences in the absolute enhancement intensity and arrival to peak time between tumor tissue and peritumoral intestinal wall （P〈0.05）. Conclusion： The intestinal malignant tumors have characteristic appearance on CEUS. The blood flow can be dynamically shown on time-intensity curve. CEUS is of clinical application value in the diagnosis of intestinal malignant tumors.

关 键 词：肠道肿瘤 超声造影 时间-强度曲线 

分 类 号：R445.1[医药卫生—影像医学与核医学]