ICU多重耐药菌的分布与耐药性分析  

Analysis on distribution and drug resistance of multidrug resistant organisms from ICU

作　　者：姚燕[1] 胡昌弟[1] 陆英[1] 

机构地区：[1]浙江省常山县人民医院检验科,浙江衢州324200

出　　处：《中国微生态学杂志》2015年第3期358-360,共3页Chinese Journal of Microecology

摘　　要：目的探讨ICU病区多重耐药菌(Multidrug resistant organism,MDRO)的分布和耐药性,为ICU患者抗感染治疗和医院感管工作提供科学依据。方法使用法国梅里埃ATB-Expression鉴定药敏分析仪完成微生物鉴定和药敏工作,回顾性分析ICU患者2011年1月至2013年12月的培养鉴定结果和药敏结果,利用WHONET 5.4软件对数据进行分析。结果共分离MDRO 432株,检出率居前三位的分别是:耐碳青霉烯类抗菌药物鲍曼不动杆菌(CR-AB,54.2%)、产超广谱β-内酰胺酶(ESBLs)细菌(23.8%)、多重耐药/泛耐药铜绿假单胞菌(MDR/PDR-PA,12.5%)。耐碳青霉烯类抗菌药物肠杆菌科细菌(CRE)的分离率逐年上升,未检出耐万古霉素肠球菌(VRE)。结论 MDRO是我院ICU病区医院感染的主要病原菌,临床应加强目标监测,控制和减少多重耐药菌在院内流行。Objective To explore the distribution and drug resistance of Multidrug-resistant organisms （MDROs） in ICU, provide scientific basis for anti-infection treatment of ICU patients and hospital infection management. Methods ATB-Expression Identification Analyzer （BioMerieux, France） was used for the identification of the microbials and drug sensitivity test. The results from January 2011 to December 2013 were retrospectively analyzed by using WHONET 5.4 software. Results 432 strains of MDROs were isolated; the top three were CR-AB （54. 2% ）, ESBLs （23. 8% ） and MDR/PDR-PA （12. 5% ）. The isolation rate of CRE had been increasing year by year, and no VRE was detected. Conclusion MDRO is the main pathogen of nosoeomial infection in ICU; monitoring should be enhanced in clinical practice in order to control and reduce the prevalence of MDROs in our hospital.

关 键 词：ICU 多重耐药菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]