膝关节镜下自体移植重建前交叉韧带的围术期感染预防研究  

Study on prevention of perioperative infections in anterior cruciate ligament rupture patients undergoing arthroscopic autograft reconstruction

作　　者：新苏雅拉图 高晓宇[1] 刘峰[1] 韩景全[1] 张虎雄[1] 

机构地区：[1]鄂尔多斯市中心医院骨一科,内蒙古鄂尔多斯017000

出　　处：《中华医院感染学杂志》2015年第9期2097-2099,共3页Chinese Journal of Nosocomiology

基　　金：内蒙古卫生厅重点基金资助项目(201001019)

摘　　要：目的探讨围术期感染在膝关节镜下自体移植重建前交叉韧带中的重要性,以提高临床诊治水平。方法选取2005年2月-2013年2月1 050例前交叉韧带断裂手术患者为研究对象,随机分组,对照组520例,予常规的关节镜下自体移植重建前交叉韧带术,观察组530例,在对照组基础上加强围术期感染预防的管理,观察治疗后在感染相关指标和临床效果。结果对照组感染率2.50%,观察组感染率0.94%,两组比较差异有统计学意义(P<0.05);对照组白细胞计数(15.54±2.34)×109/L、C-反应蛋白(63.44±21.58)mg/L、IL-1(75.68±34.31)ng/ml,观察组分别为(11.37±1.95)×109/L、(34.57±16.46)mg/L、(34.24±13.58)ng/ml,两组比较差异有统计学意义(P<0.05);对照组住院时间(12.4±3.4)d、生活质量评分(78.5±12.5)分、视觉模拟评分(6.8±2.1)分、下床活动时间(9.7±2.1)周、渗液消失时间(6.7±1.5)d,观察组分别为(10.6±2.9)d、(89.4±14.6)分、(9.5±3.1)分、(8.4±1.9)周、(5.8±1.1)d,两组比较差异有统计学意义(P<0.05)。结论围术期注重预防感染有助于提高膝关节镜下自体移植重建前交叉韧带术后的临床效果,降低并发症的发生率。OBJECTIVE To study the importance of prevention of the perioperative infections in the anterior cruciate ligament rupture patients undergoing arthroscopic autograft reconstruction so as to improve the clinical diagnosis and treatment .METHODS A total of 1 050 patients with anterior cruciate ligament rupture who were treated from Feb 2005 to Feb 2013 were recruited as the study objects and randomly divided into the control group with 520 ca‐ses and the observation group with 530 cases ;the control group was given the conventional arthroscopic autograft reconstruction for anterior cruciate ligament rupture ,while the observation group was paid high attention to the prevention of perioperative infections based on the treatment of the control group .The related indicators for the infections and the clinical effects were observed after the treatment .RESULTS The infection rate was 2 .50% in the control group ,0 .94% in the observation group ,and there was significant difference between the two groups （P〈0 .05） .The white blood cells counts were （15 .54 ± 2 .34）× 10^9/L in the control group ,（11 .37 ± 1 .95）× 10^9/L in the observation group;the level of C‐reactive protein was （63 .44 ± 21 .58）mg/L in the control group ,（34 .57 ± 16 .46）mg/L in the observation group;the level of IL‐1 was （75 .68 ± 34 .31）ng/ml in the control group ,（34 .24 ± 13 .58）ng/ml in the observation group ,and there was significant difference between the two groups （P〈0 .05） . The length of hospital stay was （12 .4 ± 3 .4） days in the control group ,（10 .6 ± 2 .9）days in the observation group;the score of life quality was （78 .5 ± 12 .5）points in the control group ,（89 .4 ± 14 .6） points in the observa‐tion group;the visual analogue scale was （6 .8 ± 2 .1） points in the control group ,（9 .5±3 .1） points in the obser‐vation group;the off‐bed ambulation time was （9 .7 ± 2 .1） weeks in the control group ,（8 .4 ± 1 .9） weeks in the observation group ;the t

关 键 词：膝关节镜 自体移植重建 前交叉韧带 围术期感染 

分 类 号：R181.32[医药卫生—流行病学]