磁共振表观扩散系数对非哺乳期乳腺炎和乳腺癌的鉴别诊断价值  

The Value of MRI Apparent Diffusion Coefficient in Differentiating Non-Puerperal Mastitis from Breast Cancer

作　　者：范光荣[1] 陈翠芬[2] 朱志军[1] 张芳璟 郭吉敏[1] 王小鹏[1] 严芳[1] 

机构地区：[1]南方医科大学附属深圳市妇幼保健院放射科,深圳518028 [2]深圳市龙岗中心医院放射科,518116

出　　处：《临床放射学杂志》2015年第4期544-547,共4页Journal of Clinical Radiology

摘　　要：目的探讨表观扩散系数(ADC)值测量对非哺乳期乳腺炎和乳腺癌的鉴别诊断价值。方法回顾性分析经病理证实的16例非哺乳期乳腺炎患者和18例乳腺癌患者的MRI、DWI表现,并测量ADC值,取对侧乳腺对应部位正常腺体ADC值作为对照组。DWI采用单次激发的平面回波(EPI)序列,b值为0 s/mm2和800 s/mm2。结果非哺乳期乳腺炎、乳腺癌和正常乳腺组织的ADC值分别为(1.44±0.51)×10-3mm2/s、(1.08±0.27)×10-3mm2/s、(1.73±0.23)×10-3mm2/s,组间差异有统计学意义(F=48.023 P=0.00),组间两两比较,各组间均有统计学意义(P<0.05)。结论 ADC值测量对非哺乳期乳腺炎和乳腺癌有重要的鉴别诊断价值。Objective To assess the clinical value of apparent diffusion coefficient （ADC） in differentiating non-puer- peral mastitis from breast cancer. Methods A total of 16 patients with pathologically-proved non-puerperal mastitis and 18 patients with pathologically-proved breast cancer were enrolled in this study. MRI and diffusion weighted imaging （DWI） were performed in all patients; ADC values were determined. The ADC values of the corresponding parts of the normal contralateral breast gland were used as the control group. DWI, using single shot EPI sequence with b values of 0 mm^2/s and 800 mm^2/s, was employed in all patients. Results The mean ADC values of non-puerperal mastitis group, breast cancer group and normal breast gland group were （ 1.44 ±0.51 ） ×10^-3mm^2/s, （ 1.08 ±0.27 ） ×10^-3mm^2/s and （ 1.73 ±0.23 ） ×10^-3mm^2/s respectively. The differences between each other among the three groups were statistically significant （F =48. 023, P =0.00, one-way ANOVA）. Moreover, statistical significant differences also existed between every two groups （ P 〈 0.05 ）. Conclusion ADC has an important differential diagnostic value for non-puerperal mastitis and breast cancer.

关 键 词：非哺乳期乳腺炎 乳腺癌 表观扩散系数 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R655.8[医药卫生—诊断学] R737.9[医药卫生—临床医学]