WHO甲状腺容积标准判定高碘甲状腺肿大适用性的探讨  

Exploration on the feasibility of judging high iodine goiter by the WHO thyroid volume criteria

作　　者：吕胜敏[1] 徐栋[1] 王玉春[2] 杜永贵[1] 贾丽辉[1] 马景[1] 赵君[1] 

机构地区：[1]河北省疾病预防控制中心,河北石家庄050021 [2]衡水市疾病预防控制中心

出　　处：《中国地方病防治》2015年第2期92-94,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：目的探讨WHO甲状腺容积标准对我国儿童高碘甲状腺肿大的适用性。方法在河北省衡水市随机选取3个水碘中位数在150-300μg/L的高碘乡和1个水碘中位数为105.4μg/L的对照乡,采用单纯随机抽样方法,分别在3个高碘乡和对照乡选取452名和120名8-10岁儿童,用B超测量其甲状腺容积,用WHO和我国甲状腺容积标准判定其甲状腺肿大情况。结果 WHO和我国甲状腺容积标准判定的3个高碘乡儿童甲状腺肿大率为24.6%（111/452）和8.2%（37/452）,有显著统计学差异（χ^2=44.19,P=0）。两个标准判定的8、9、10岁年龄组肿大率分别为33.7%（31/92）、23.3%（45/193）、21.0%（35/167）和14.1%（13/92）、6.2%（12/193）、7.2%（12/167）;男孩和女孩的肿大率分别为27.1%（66/244）、21.6%（45/208）和7.4%（18/244）、9.1%（19/208）;均有显著统计学差异。对照乡儿童甲状腺肿大率分别为14.0%（17/120）和4.2%（5/120）,有显著差异（χ^2=7.18,P=0.007）。结论判定高碘甲状腺肿大时,WHO甲状腺容积标准对我国儿童偏低。Objective To explore the feasibility of judging high iodine goiter using the WHO thyroid volume criteria in Chinese children. Methods Three towns with median water iodine （MWI） of 150 - 300 p,g/L were selected randomly in Hengshui city of Hebei province of China, and one town with MWI being 105.4 μg/L was chosen as control. A total of 452 children in the three towns and 120 children in the control town were randomly selected to measure thyroid volume by ultrasound. Their goiter status was judged using the WHO and Chinese criteria, respectively. Results Judged by the WHO and national thyroid volume criteria, the overall goiter prevalence in the three towns was 24.6% （111/452） and 8.2% （37/452）, with significant difference （χ^2 =44.19, P =0）. The goiter prevalence by the two criteria in the age group of 8, 9, 10 years old was 33.7% （31/92）, 23.3% （45/193）, 21.0% （35/167） and 14.1% （13/92）, 6.2% （12/193）, 7.2% （12/167）. The differences in goiter prevalence were all significant. The children＇s goiter prevalence in the control town was 14.0% （17/120） and 4.2% （5/120）, with significant difference （χ^2= 7.18, P = 0. 007）. Conclusion Judging high iodine goiter, the WHO criteria may be a little low for Chinese children.

关 键 词：碘过量 高碘 甲状腺肿 甲状腺容积 标准 

分 类 号：R581.3[医药卫生—内分泌]