梅毒患者血清IL-33和IL-35与梅毒细胞免疫的相关性  

The relevance of serum levels of IL-33 and IL-35 with profeta's immunity in the patients with syphilis

作　　者：张胜佳[1] 田洪青[2] 李中伟[2] 郑荣涛[2] 侯建玲[2] 李富容[2] 

机构地区：[1]济南大学山东省医学科学院医学与生命科学学院 [2]山东省皮肤病性病防治研究所,济南250022

出　　处：《中国麻风皮肤病杂志》2015年第4期209-211,252,共4页China Journal of Leprosy and Skin Diseases

基　　金：山东省自然科学基金(编号:ZR2013HM076)

摘　　要：目的:检测梅毒患者血清IL-33和IL-35的表达。方法:采用酶联免疫吸附法(ELISA)检测梅毒患者和正常对照血清IL-33和IL-35的表达。结果:梅毒患者血清IL-33和IL-35的表达与对照比较,差异均无统计学意义(P=0.638和P=0.122)。一期梅毒、二期梅毒、潜伏梅毒间IL-33和IL-35比较差异亦无统计学意义(P=0.116,P=0.132)。结论:梅毒患者外周血清IL-33和IL-35可能与梅毒的细胞免疫无相关性。Objective：To detect the levels of IL-33 and IL-35 in the patients with syphilis. Methods：The levels of IL-33 and IL-35 in the patients and healthy controls were detected with ELISA. Results：There was no significant difference in the levels of IL-33 and IL-35 between the patients and controls （ P=0.63 and P=0.122） . There were no significant difference in the levels of IL-33 and IL-35 among primary syphilis, secondary syphilis and latent syphilis. Conclusion：IL-33 and IL-35 may not correlate with the cellular im-munity in the patients with syphylis.

关 键 词：梅毒 细胞免疫 白介素33 白介素35 IL-33 IL-35 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]