11例嗜酸性脂膜炎临床分析  被引量:1

Clinical analysis of 11 patients with eosinophilic panniculitis

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作  者:徐俊涛[1] 刘菡[1] 周慧[2] 

机构地区:[1]湖北医药学院附属东风医院皮肤科,湖北十堰442008 [2]湖北医药学院附属东风医院输液室,湖北十堰442008

出  处:《中国麻风皮肤病杂志》2015年第4期221-222,共2页China Journal of Leprosy and Skin Diseases

摘  要:对11例嗜酸性脂膜炎患者的临床资料进行分析,临床表现为皮下结节/斑块8例;溃疡2例,紫癜、水疱、血疱、坏死及糜烂1例。伴发热1例,内脏受累7例,浅表淋巴结肿大5例,关节受累2例。给予口服糖皮质激素(泼尼松30~50 mg/d)和环孢素(5 mg/kg·d),结节皮损内注射干扰素(300万U/次,每周1次)治疗。随访3~60个月后,临床治愈8例,好转2例,停药后复发1例。The data of 11 patients with eosinophilic panniculitis (EP) were analysed. The clinical mani-festations were single subcutaneous nodule/plaque in 8 patients and ulcer in 2. One patient had variety of le-sions including purpura, vesicle, hemorrhagic vesicle, necrosis and erosion. In addition, there was fever in 1 patient, internal organs involvement in 7, lymphadenectasis in 5, joints involvement in 7. Those patients were treated with oral glucocorticoids ( prednisone 30~50 mg/d) and cyclosporine A ( 5 mg/kg·d) and subcutane-ous nodule injection of interferon ( 3 million IU, once a week) . Eight patients were cured, 2 patients got better and 1 patient relapsed after 3~60 months follow-up.

关 键 词:嗜酸性脂膜炎 临床 预后 

分 类 号:R597[医药卫生—内科学]

 

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