川芎嗪保守治疗Ⅲ期糖尿病视网膜病患者的可行性分析  

Ligustrazine Conservative Treatment of StageⅢ Feasibility Analysis of Diabetic Retinal Disease

作　　者：邓亚玲[1] 

机构地区：[1]广东省深圳市第三人民医院眼科,518000

出　　处：《医学理论与实践》2015年第7期855-856,共2页The Journal of Medical Theory and Practice

摘　　要：目的:分析川芎嗪保守治疗Ⅲ期糖尿病视网膜病患者的可行性。方法:选取我院Ⅲ期DR患者70例,随机分为观察组和对照组各35例,两组均给予降糖药物的持续应用、维脑路通、云南白药、维生素类、糖尿病饮食、活动指导等治疗方案,观察组在此基础上给予川芎嗪静脉滴注。观察两组患者治疗后有效率以及疾病进展情况。结果:观察组总有效率94.3%,对照组总有效率71.4%,两组总有效率经统计学分析,P<0.05差异具有统计学意义。单从疾病进展情况来看,观察组患者无1例进展,对照组6例出现PDR,后行玻璃体切除术,视力下降明显。两组疾病进展情况经统计学分析,P<0.05,差异具有统计学意义。结论:川芎嗪治疗DR-Ⅲ患者疗效显著,且能控制病情进一步发展,但其不良反应尚需进一步观察。因此应用川芎嗪治疗DR-Ⅲ患者具有一定的可行性。Objective ：To analyze ligustrazine conservative treatment of stage Ⅲ the feasibility of diabetic retinal dis‐ease .Methods ：Select our hospital patients with stage Ⅲ DR 70 cases were randomly divided into observation group and control group ,35 cases in the two groups for continuous use of hypoglycemic drugs ,Venoruton ,yunnan baiyao ,vita‐mins ,diabetes diet ,activities to guide treatment ,observation group on the basis of ligustrazine intravenous drip .Effi‐cient after observing two groups of patients ,and two groups of patients with the progress of the disease .Results：Ob‐servation group total effectiveness 94 .3% ,control group total effective rate 71 .4% ,two groups total effective rate af‐ter statistics analysis ,P〈0 .05 difference is statistically significant .Single from the progress of the disease ,observation group of patients with no progress in 1 case and control group in 6 cases of PDR ,after vitrectomy ,decreased vision . Two groups of the progress of the disease by the statistical analysis ,P〈0 .05 ,the difference is statistically significant . Conclusion：Ligustrazine DR‐Ⅲ patients with obvious therapeutic effect ,and further development to further control the condition ,but the adverse reaction still needs further observation .So DR‐Ⅲpatients treated in application of ligustrazine has certain feasibility .

关 键 词：川芎嗪 糖尿病视网膜病 缺血再灌注损伤 

分 类 号：R587.2[医药卫生—内分泌]