不同雾化吸入诱导吸痰对痰标本量和痰检结果影响  

Effects of atomization inhalation of hypertonic saline solution and chymotrypsin solution on sputum analysis for detecting lung cancer cell

作　　者：张秀美[1] 王彦[1] 李娜[1] 崔婷[1] 倪胜贤 黄以羚 

机构地区：[1]上海交通大学附属第一人民医院分院,上海200081

出　　处：《上海护理》2015年第3期16-18,共3页Shanghai Nursing

基　　金：上海市虹口区卫生局重点课题(虹卫1302-04)

摘　　要：目的比较高渗盐水与糜蛋白酶雾化吸入诱导吸痰对痰标本量和痰检结果的影响。方法选取2013年8月—2015年2月在上海交通大学附属第一人民医院分院拟诊肺癌患者60例,随机分为高渗盐水组29例和糜蛋白酶组31例,分别雾化吸入后留痰送检,以纤维支气管镜检查、穿刺活检或术后病理为对照标准,比较两组患者痰标本量和肺癌检出率的差异。结果高渗盐水组平均收集痰液量显著多于糜蛋白酶组(P<0.05),高渗盐水组留痰标本合格率显著高于糜蛋白酶组(P<0.05),两组痰检肺癌的检出率分别是77.8%和43.6%,差异有统计学意义(P<0.05)。结论高渗盐水雾化吸入诱导吸痰能规范送检痰标本的质量,提高痰检的效果,有利于疾病的诊断。Objective To compare the effects of atomization inhalation of hypertonie saline solution and chymotrypsin solution on sputum analysis for detecting lung cancer cell. Methods Sixty cases with suspected lung cancer in Branch of Shanghai First People＇s Hospital, Shanghai Jiao Tong University were enrolled from August 2013 to February 2015. They were randomly divided into the hypertonic saline group （n = 29） and the chymotrypsin group （ n = 31 ）. The lung cancer cell detection was performed by collecting sputum with atomization inhalation of hypertonic saline solution and chymotrypsin solution. The sputum analysis results were proved by fibrobrochoscope, biopsy or postoperative pathology. Results The average amount of collected sputum in the hypertonic saline group was significantly more than that in the chymotrypsin group （ P 〈 0.05 ）. The qualified rate of sputum specimens in the hypertonic saline group was significantly higher than that in the chymotrypsin group （ P 〈 0.05 ）. The detection rates of lung cancer cell were 77.8% and 43.6% in the hypertonic saline group and the chymotrypsin group, respectively. There was significant difference between the two groups （ P 〈 0. 05 ）. Conclusion Atomization inhalation of hypertonic saline solution is better than chymotrypsin solution in collecting sputum for detecting lung cancer cell.

关 键 词：肺癌 痰检 雾化吸入 诱导吸痰 

分 类 号：R47[医药卫生—护理学]