Pleiotrophin fights Brd2 for neuronal differentiation  

作　　者：Pablo Garcia-Gutierrez Mario Garcia-Dominguez 

机构地区：[1]Stem Cells Department,Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) (Consejo Superior de Investigaciones Cientificas (CSIC),Junta de Andalucía,Universidad de Sevilla,Universidad Pablo de Olavide).Av.Americo Vespucio s/n,41092 Seville,Spain

出　　处：《Neural Regeneration Research》2015年第4期544-546,共3页中国神经再生研究（英文版）

基　　金：supported by Ministry of Economy and Competitiveness,Spain(MINECO),grant number BFU2012-37304;by Junta de Andalucía,Spain,grant number P12-CTS-2064

摘　　要：Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.

关 键 词：Pleiotrophin fights Brd2 for neuronal differentiation CYCLE 

分 类 号：R338[医药卫生—人体生理学]