单用依托咪酯或丙泊酚诱导插管在急诊危重患者中的临床观察  

Clinical observation on emergency intubation in critically ill patients with single use of etomidate or propofol induction

作　　者：杨秋燕[1] 赵映红 麦超[1] 曹小平[1] 

机构地区：[1]川北医学院附属医院急诊科 [2]湖北省孝感市95829部队司令部门诊部

出　　处：《川北医学院学报》2015年第2期170-172,共3页Journal of North Sichuan Medical College

基　　金：四川省教育厅科研项目(10ZA076)

摘　　要：目的:探讨单用依托咪酯或丙泊酚诱导气管插管在急诊危重患者中的可行性和安全性。方法:回顾性分析单用依托咪酯或丙泊酚诱导气管插管的首次成功率、反流误吸发生率、诱导后低血压和心律失常发生率、气管插管后药物的使用情况。结果:所有患者在诱导插管过程中都无反流误吸发生。与丙泊酚诱导比较,依托咪酯诱导低血压与心律失常发生率更低,插管后升压药物使用率更低(P<0.05)。首次成功率和降压药使用率差异无统计学意义。结论:急诊危重病患者单用依托咪酯或丙泊酚诱导气管插管都具有良好可行性,但用依托咪酯诱导插管更安全。Objective： To explore the safety of etomidate and propofol induction and tracheal intubation in critically ill pa-tients. Methods：Retrospectively analyze the single use of etomidate or propofol for induction and intubation. The first time success rate, incidence of regurgitation and aspiration,induced hypotension and arrhythmia and the drug use after tracheal intubation were observed. Results：All patients in the process of induction and tracheal intubation had no aspiration occurred. Compared with propofol group,lower incidence of induced hypotension and arrhythmia was observed in etomidate group. After intubation,vasopressor use rate is lower in eto-midate group （P〈0. 05）. The first success rate and hypotensor use rate had no significant difference. Conclusion：Treating emergency critically ill patients with single use of etomidate or propofol has good feasibility for tracheal intubation,while etomidate induction has more security.

关 键 词：依托咪酯 丙泊酚 气管插管 危重病患者 

分 类 号：R614.2[医药卫生—麻醉学]