清肝化瘀方水提工艺优选  

Optimization of the Water Extraction Process for Qinggan Huayu Recipe

作　　者：吴桐[1] 张相林[2] 宋威江[1] 李蕊[1] 姚树坤[1,2] 

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院,北京100029

出　　处：《现代中药研究与实践》2015年第2期38-40,49,共4页Research and Practice on Chinese Medicines

基　　金：国家重大新药创制专项课题(2012ZX09103201-021)

摘　　要：目的优化清肝化瘀方最佳水提工艺。方法采用正交试验法,以总黄酮含量、野黄芩苷含量、干膏得率为指标,考察加水倍数、提取时间、提取次数对水提工艺的影响,优选出最佳工艺。结果最佳水提工艺为12倍水量,提取2 h,提取3次。结论该提取方法所得总黄酮含量较高,且工艺稳定可行。Objective To optimize the water extraction process for Qinggan Huayu Recipe. Methods Using orthogonal design method,taking flavonoids content, scutellarin content and dryextractyield rate as the index, studying the effection of ratio of water to liquid,extraction durations and extraction times on water extraction process to select the best technology. Results The optimum process was 12 times water, extraction 3 times ,each 2 hours. Conclusion There are higher total flavonoids content by the extraction method, and the process is stable and feasible.

关 键 词：清肝化瘀方 水提工艺 总黄酮 野黄芩苷 

分 类 号：R284.2[医药卫生—中药学]