新生儿院内感染肺炎克雷伯菌败血症11例临床分析  

Clinical analysis of nosocomial neonatal septicemia caused by klebsiella pneumonia in 11 cases

作　　者：张国宪[1] 郭少辉[1] 彭丽娜[1] 陈海花[1] 

机构地区：[1]河南宏力医院新生儿科,河南长垣453400

出　　处：《中国医药科学》2015年第6期57-58,64,共3页China Medicine And Pharmacy

摘　　要：目的探讨我院NICU院内感染肺炎克雷伯菌败血症的临床特点及药敏情况,为早期诊断合理治疗提供依据。方法对我院NICU 11例确诊为院内感染肺炎克雷伯菌败血症的新生儿资料进行临床特点及药敏结果的回顾性分析。结果肺炎克雷伯菌败血症多见于早产儿,病情进展快,易造成多脏器功能损害;以产ESBLS菌株为主,耐药性强,对一般常用抗生素不敏感。结论新生儿尤其早产儿院内感染应重视肺炎克雷伯菌败血症,首选碳青霉烯类如亚胺培南及美罗培南治疗,以尽早控制疾病发展,降低病死率。Objective To study the clinical effect and the drug sensitivity of nosocomial neonatal septicemia caused by klebsiella pneumonia in neonatal intensive care unit （NICU） to provide evidence for early diagnosis and reasonable treatment. Methods To retrospectively analyze the clinical effect and the drug sensitivity of 11 cases of nosocomial neonatal septicemia caused by klebsiella pneumonia in NICU of our hospital. Results Septicemia caused by klebsiella pneumonia which was more common in premature infants was easy to cause multiple organ damage, to malnly produce ESBLS, has strong drug resistance and was insensitive to the commonly used antibiotics. Conclusion Nosocomial neonatal specially premature infants should to emphasize the septicemia which caused by klebsiella pneumonia, to treat with carbapenems such as imipenem and meropenem, to control the disease development and to reduce the fatality rate.

关 键 词：新生儿 败血症 院内感染 肺炎克雷伯菌 

分 类 号：R725.6[医药卫生—儿科]