穴位埋线治疗肾虚肝郁证围绝经期轻度抑郁患者临床观察  

Clinical observation on mild perimenopausal depression of kidney deficiency and liver stagnation syndrome treated with acupoint catgut implantation

作　　者：孙占玲[1] 金亚蓓[1] 项洪艳[2] 刘芳[1] 

机构地区：[1]浙江省中西医结合医院针灸科,杭州310003 [2]海宁市中医院

出　　处：《中国针灸》2015年第5期443-446,共4页Chinese Acupuncture & Moxibustion

基　　金：浙江省中医药科学研究基金计划项目:2010ZA098

摘　　要：目的:观察穴位埋线治疗肾虚肝郁证围绝经期轻度抑郁的临床疗效,并分析其主要作用的靶症状群。方法:将45例患者随机分为埋线组(23例)和针刺组(22例),埋线组取肾俞、肝俞、心俞、脾俞等穴进行埋线,每周1次;针刺组取埋线组相同穴位常规针刺,隔日1次,均以4周为一疗程,连续治疗2个疗程,2个疗程后进行疗效评价,第12周进行随访。观察患者治疗前后及随访时Kupperman评分、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)总分和因子评分的变化。结果:治疗后两组Kupperman评分、HAMD总分及焦虑/躯体化、阻滞、睡眠障碍和认知障碍评分均较治疗前显著降低(P<0.01,P<0.05);随访时,埋线组Kupperman评分与治疗后比较差异无统计学意义(P>0.05),HAMD总分和睡眠障碍评分较治疗后显著降低(均P<0.01);针刺组随访时Kupperman评分、HAMD总分和睡眠障碍评分均较治疗后升高(均P<0.05);埋线组HAMD总分低于针刺组(P<0.05),其阻滞和睡眠障碍评分亦较针刺组显著降低(均P<0.01)。结论:穴位埋线能减轻肾虚肝郁证围绝经期轻度抑郁患者的围绝经期症状,并通过对焦虑/躯体化、阻滞、睡眠障碍和认知障碍等靶症状群的调节,有效缓解患者的抑郁情绪,远期疗效优于常规针刺。Objective To observe the efficacy of catgut implantation at back-shu points in treatment of mild perimenopausal depression of kidney deficiency and liver stagnation syndrome and analyze its essential function on target symptoms.Methods Forty-five cases were randomized into a catgut implantation group（23cases）and an acupuncture group（22cases）.In the catgut implantation group,catguts were implanted at Shenshu（BL 23）,Ganshu（BL 18）,Xinshu（BL 15）,Pishu（BL 20）,etc.,once every week.In the acupuncture group,the conventional acupuncture was applied to the same acupoints as the catgut implantation group,once every two days.The treatment of 4weeks made one session,and continuous 2sessions were required.The efficacy was evaluated in2 sessions.The follow-up started in the 12 th week.Before treatment,after treatment and in the follow-up period,Kupperman score and the total score in Hamilton depression scale（HAMD）,as well as the factor score were observed in the patients separately.Results Kupperman score,the total HAMD score and the scores in the items of anxiety/somatization,retardation,sleep disorder and cognitive disorder after treatment were all reduced significantly as compared with those before treatment in the two groups（P〈0.01,P〈0.05）.In the follow-up period,the difference in Kupperman was not significant in comparison with that after treatment in the catgut implantation group（P〉0.05）.The total HAMD score and sleep disorder were reduced significantly as compared with those after treatment in the catgut implantation group（both P〈0.01）;in the acupuncture group,Kupperman score,the total HAMD score and sleep disorder were all increased as compared with those after treatment（all P〈0.05）.In the catgut implantation group,the total HAMD score was lower than that in the acupuncture group（P〈0.05）,and the scores in the items of retardation and sleep disorder were reduced significantly as compared with those in the acupuncture group（both P〈0.01）.Conclusion The catgu

关 键 词：围绝经期抑郁 肾虚肝郁证 背俞穴 埋线疗法 Kupperman HAMD 随机对照试验 

分 类 号：R246.3[医药卫生—针灸推拿学]