2型糖尿病患者低血糖恐惧感现状及相关因素研究  

Status and influencing factors of fear of hypoglycemia among patients with type 2 diabetes mellitus

作　　者：穆纯 包頔 王美君[1] 邢秋玲[1] 

机构地区：[1]天津医科大学代谢病医院 卫生部激素与发育重点实验室,300070

出　　处：《中华糖尿病杂志》2015年第4期235-240,共6页CHINESE JOURNAL OF DIABETES MELLITUS

摘　　要：目的：调查有低血糖史的2型糖尿病（T2DM）住院患者低血糖恐惧感现状并分析其影响因素。方法采用多中心、目的抽样方法，选取2014年2至8月于天津市5家3级甲等医院就诊的396例T2DM住院患者作为研究对象。应用一般资料调查表、中文版低血糖恐惧调查表（CHFSII-WS）、焦虑自评量表、抑郁自评量表对患者进行问卷调查。本研究对二分类变量间的比较采用独立样本t检验，多分类变量间的比较采用F检验，对低血糖恐惧感的影响因素分析采用多元线性回归方法进行统计分析。结果396例患者[其中男性218例，女性178例,平均年龄（55±9）岁] CHFSII-WS评分中位数为9分（四分位间距，5-16分）。单因素分析中，性别、家族史、焦虑评分、抑郁评分（t=-3.797、2.010、3.809、3.479）差异有统计学意义（均P〈0.05）；婚姻状况、低血糖发生频次、低血糖严重程度的患者的低血糖恐惧感评分差异具有统计学意义（F=6.617、2.644、3.327、3.246；均P〈0.05）。多元线性回归分析显示，低血糖恐惧感的影响因素为严重低血糖、焦虑、性别、离异、低血糖发生频率（调整R^2=0.229，F=5.905，t=3.935、2.179、2.488、2.443、2.1199，均P〈0.05）。结论在临床工作中，医护人员应注重对发生低血糖的T2DM患者进行低血糖恐惧感评估，并给予患者关于低血糖的健康指导。Objective To investigate the current status of the fear of hypoglycemia in hospitalized type 2 diabetes mellitus with the history of hypoglycemia. Mehtods Total of 396 type 2 diabetes patients with the history of hypoglycemia were recruited by multi-centers purposive sampling method. The Mean （SD） age of the 396 participants was 55.4（9.34） years, 218 being male. The subjects were investigated with Chinese version of Hypoglycemia Fear SurveyII-Worry Scale （CHFSII-WS）, self-rating depression scale （SDS）, self-rating anxiety scale（SAS） and demographic survey questionnaire. T test and one-way AVOVA and multiple linear regression analysis were used to analyze the data. Results The median score of CHFSII-WS was 9.00 points （interquartile range, 5-16 points）. The t-test showed that the scores of CHFSII-WS was significantly associated with gender, family history, anxiety and depression （t=-3.797,2.010,3.809,3.479, all P〈0.05）. The F-test showed that age, marital status, frequency of hypoglycemia, severity of hypoglycemia （F=6.617,2.644,3.327,3.246, all P〈0.05） were significantly associated with the scores of CHFSII-WS. Regression analysis showed that severe hypolycemia, anxiety, female, divorced and the frequency of hypoglycemia were significant factors of patients′ fear of hypoglycemia （adjusted R^2=0.229,F=5.905,P〈0.05）. Conclusions In the clinical practice, the nursing stuff should pay attention to the evaluation of the patients′fear of the hypoglycemia and provide the health education of hypoglycemia in patients with type 2 diabetes.

关 键 词：糖尿病 2型 低血糖 低血糖恐惧感 DIABETES mellitus type 2 

分 类 号：R587.1[医药卫生—内分泌]