先兆性偏头痛患者二尖瓣及主动脉瓣纤维性丝状物的发生情况  

Incidences of Aortic and Mitral Valve Strands in Patients with Migraine with Aura

作　　者：翟亚楠[1] 李越[1] 魏丽群[1] 张梅青[2] 卢宏泉[1] 张丽[1] 

机构地区：[1]中国人民解放军总医院超声诊断科,北京100853 [2]中国人民解放军总医院第一附属医院心内科,北京100048

出　　处：《中国医学科学院学报》2015年第2期147-151,共5页Acta Academiae Medicinae Sinicae

摘　　要：目的分析二尖瓣与主动脉瓣纤维性丝状物是否与先兆性偏头痛有关。方法先兆性偏头痛患者51例,同时选取无偏头痛因其他问题需要经食管超声心动图检查者75例作为对照组。常规经食管超声心动图检查,观察二尖瓣和/或主动脉瓣上是否存在微细、摆动的丝状回声。结果先兆性偏头痛组与对照组左心瓣膜纤维性丝状物存在率分别为21.5%(11/51)和28.0%(21/75),两组比较差异无统计学意义(χ2=0.663,P=0.416)。先兆性偏头痛组与对照组二尖瓣纤维性丝状物存在率分别为5.8%(3/51)和13.3%(10/75),两组比较差异无统计学意义(χ2=1.821,P=0.177)。先兆性偏头痛组与对照组主动脉瓣纤维性丝状物存在率分别为19.6%(10/51)和25.3%(19/75),两组比较差异无统计学意义(χ2=0.562,P=0.454)。先兆性偏头痛组与对照组卵圆孔未闭发生率分别为50.9%(26/51)和29.3%(22/75),两组比较差异有统计学意义(χ2=6.302,P=0.012)。先兆性偏头痛组主动脉瓣纤维性丝状物存在率显著高于二尖瓣纤维性丝状物存在率(χ2=4.320,P=0.038)。结论二尖瓣及主动脉瓣纤维性丝状物与先兆性偏头痛无明确关系,瓣膜纤维性丝状物属于良性变异可能性大。Objective To analyze the potential association between valvular strands and migraine with aura. Methods During a 1-year period,transesophageal echocardiography was performed in 51 consecutive patients with migraine with aura and 75 control subjects who underwent transesophageal echocardiography for other purposes and had no history of migraine. The presence of aortic and mitral valve strands was evaluated. Results The incidence of valvular strands was 21. 5%（ 11 /51） in migraine patients and 28. 0%（ 21 /75） in control subjects（ χ2= 0. 663,P = 0. 416）. The incidence of patent foramen ovale was significantly higher in patients with migraine with aura than in control subjects（ 50. 9% vs. 29. 3%）（ χ2= 6. 302,P = 0. 012）. The incidence of aortic valve strands was significantly higher than that of mitral valve strands in migraine patients（ χ2=4. 320,P = 0. 038）. Conclusion Valvular strands are not associated with migraine with aura and show little clinical significance.

关 键 词：瓣膜纤维性丝状物 超声心动图描记术 先兆性偏头痛 

分 类 号：R445.1[医药卫生—影像医学与核医学] R747.2[医药卫生—诊断学]