门冬胰岛素和生物合成人胰岛素治疗妊娠期糖尿病的临床疗效观察  

Observation on the clinical effect of insulin aspart and biosynthetic human insulin in treatment of gestational diabetes mellitus

作　　者：胡昭怡[1] 

机构地区：[1]广东省江门市妇幼保健院,529000

出　　处：《中国妇幼保健》2015年第15期2331-2332,共2页Maternal and Child Health Care of China

摘　　要：目的:探究临床有效治疗妊娠期糖尿病的可靠方法。方法:对84例妊娠期糖尿病患者随机分为观察组(采用门冬胰岛素诺和锐进行治疗)和对照组(采用生物合成人胰岛素诺和灵R进行治疗)各42例,观察比较两组患者临床治疗后FPG、2Hppg、Hb Alc、胰岛素用量和达标时间。结果:在FPG、2Hppg、Hb Alc、胰岛素用量、达标时间等5项指标上观察组均明显的优于对照组,差异有统计学意义(P<0.05);总低血糖发生率观察组显著的低于对照组,差异有统计学意义(P<0.01)。结论:在临床针对妊娠期糖尿病患者采用门冬胰岛素进行治疗的临床优势明显,相关患者的临床指标水平更好,不良反应发生水平更低,是临床治疗妊娠期糖尿病的理想选择。Objective： To explore the effective and reliable method for treatment of gestational diabetes mellitus （GDM） . Meth- otis： Eighty-four GDM patients were randomly divided into observation group and control group, 42 patients in observation group were trea- ted with insulin aspart, while 42 patients in control group were treated with biosynthetic human insulin ; the levels of fasting plasma glucose （FPG）, two-hour postprandial plasma glucose （2Hppg）, glycosylated hemoglobin （HbAlc）, insulin doses, and the time of reaching the standard in the two groups were observed and compared. Results： FPG, 2Hppg, HbAlc, insulin dose and the time of reaching the standard in observation group were statistically significantly better than those in control group （ P〈0. 05 ） ; the incidence rate of hypoglycemia in obser- vation group was statistically significantly lower than that in control group （P〈0. 01 ） . Conclusion： The clinical advantages of insulin as- part in treatment of GDM patients are significant, the clinical indexes are better, the incidence rates of adverse reactions are lower, which is the ideal choice for clinical treatment of GDM.

关 键 词：门冬胰岛素 生物合成人胰岛素 妊娠期糖尿病 

分 类 号：R714.256[医药卫生—妇产科学]