糖尿病肾病中医证素分布规律研究  

Distribution of TCM syndrome elements in patients with diabetic nephropathy: a literature review

作　　者：孙超[1] 谢晴宇[2] 孟庆刚[1] 

机构地区：[1]北京中医药大学,北京100029 [2]中国中医科学院中医临床基础医学研究所

出　　处：《北京中医药大学学报》2015年第4期266-270,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(No.81273876);高等学校博士点基金项目(No.20110013110001);北京中医药大学创新团队项目(No.2011-CXTD-03)

摘　　要：目的以中医药辨证论治糖尿病肾病的期刊文献资料为研究对象,考察糖尿病肾病中医证素分布情况。方法检索中国期刊数据库(CNKI)、万方数据知识服务平台、维普数据库从建库至2014年8月9日糖尿病肾病中医辨证分型的文献。最终纳入相关文献159篇(单纯辨证分型文献111篇,辨证分型结合疾病分期文献48篇),分别统计病性证素和病位证素出现的频数。结果单纯辨证分型中糖尿病肾病病位主要在肾、脾;病性以虚证为主,阴虚所占比例最高。结合疾病分期辨证分型中前期和早期糖尿病肾病病位主要在肾、脾、肝,病性以阴虚为主;中期病位在肾、脾,病性以阳虚、气虚、阴虚并存;晚期病位在肾、脾,病性以阴阳两虚为主。结论通过文献研究糖尿病肾病的中医证素分布,有利于统一及标准化中医辨证分型,为临床提供参考。Objective To reveal the distribution of the TCM nephropathy （DN）, by searching the literature of TCM diagnosis syndrome elements in patients with diabetic and treatment on DN. Methods Relevant literatures on treating DN by syndrome differentiation of TCM were retrieved in CNKI, Wangfang Data and VIP from the beginning to August 9th, 2014. Syndrome elements of disease nature or of disease location were analyzed from 159 eligible literature divided into two parts： syndrome differentiation only （n = 111 ） and syndrome differentiation combined with clinical stage （n = 48）. Results From the litrature of syndrome differentiation only, kidney and spleen were the most common syndrome elements of disease location, while yin deficiency was the most common syndrome elements of disease nature. By the contrast, from the literature of syndrome differentiation combined with clinical stage, the main syndrome elements of location were kidney, spleen and liver and the most common syndrome element of nature was yin deficiency at early stage ; at middle stage, the main elements of location were kidney and spleen and of nature was deficiency syndrome including yin deficiency, yang deficiency and qi deficiency; at end stage, the main elements of location were still kidney and spleen and of nature was yin-yang deficiency. Conclusion Study on syndrome elements of DN from literature is favorable for standardization of clinical syndrome differentiation and providing reference for therapy.

关 键 词：糖尿病肾病 文献资料 病性证素 病位证素 

分 类 号：R214.4[医药卫生—中医学]