3673例人乳头瘤病毒感染的相关因素分析  

Analysis on related factors of 3 673 cases of human papillomavirus infection

作　　者：陈旭华 李云香[2] 

机构地区：[1]广东省惠州市第六人民医院检验科,516211 [2]广东省惠州市第二妇幼保健院检验科,516001

出　　处：《检验医学与临床》2015年第9期1220-1222,共3页Laboratory Medicine and Clinic

基　　金：广东省惠州市科技计划项目(2014Y192)

摘　　要：目的分析惠州市人乳头瘤病毒(HPV)感染的相关因素,为临床防治提供依据。方法回顾性分析惠州市3 673例HPV感染病例,并以无HPV感染女性作为对照,分析受检者一般资料、性生活情况、孕产情况等。结果单因素分析,初次性生活年龄、性伴侣数、配偶性伴侣数、吸烟、性伴侣吸烟、孕次、产次、流产次数、畸胎史及避孕套使用比较两组差异有统计学意义(P<0.05);但口服避孕药及合并HPV感染以外的其他性传播疾病比较差异无统计学意义(P>0.05)。多因素分析,初次性生活年龄、性伴侣数、配偶性伴侣数、流产次数、畸胎史及避孕套使用为HPV感染的危险因素。结论应加大宣传力度,使更多女性认识到HPV感染的主要途径,减少性伴侣,安全性行为,并了解预防措施,实现防治结合;同时应加大临床筛查力度和丰富筛查手段。Objective To analyze the relevant factors of human papillomavirus（HPV） infection in Huizhou cit‐y to provide the basis for its clinical prevention and treatment .Methods 3 673 cases of HPV infections in Huizhou city were retrospectively analyzed with women without HPV infection as controls .The general information ,sexual life ,motherhood situation ,etc .were analyzed .Results The univariate analysis showed that the first time of sexual life age ,number of sexual partners ,spouses number of sexual partners ,smoking ,sexual partners of smoking ,gravidi‐ty ,parity ,number of miscarriages ,birth defects and condom use history had statistical differences between the two groups （P〈0 .05）;but there was no statistically significant difference in other sexually transmitted diseases outside oral contraceptives and combined HPV infection （P〉0 .05） .The multivariate analysis showed that the first time of sexual life age ,number of sexual partners ,spouses number of sexual partners ,number of abortions ,birth defects and condom use history were the risk factors for HPV infection .Conclusion The publicity efforts should be increased to make more women to realize the main pathway of HPV infection ,reduce sexual partners ,practise safe sex ,and learn the preventive measures for achieving the combination of prevention and treatment ;should simultaneously increase the clinical screening efforts and enrich the clinical screening means .

关 键 词：人乳头瘤病毒 相关因素分析 宫颈癌 流行病学 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]