血清胰岛素与C肽测定在新生儿低血糖诊断中的临床意义  

Clinical significance of serum insulin and C-peptide measurement in diagnosis of neonatal hypoglycemia

作　　者：朱伟娜[1] 郭淑芹[2] 李志红[2] 杨彩珍[3] 田晓宁[4] 杨梅[1] 

机构地区：[1]河北省保定市第一中心医院新生儿科,071000 [2]河北省保定市第一中心医院内分泌科,071000 [3]河北省保定市第一中心医院儿科,071000 [4]河北省保定市第一中心医院医务科,071000

出　　处：《检验医学与临床》2015年第9期1223-1224,1227,共3页Laboratory Medicine and Clinic

基　　金：吴阶平医学基金会临床科研专项资助基金(320.6750.14153)

摘　　要：目的探讨血清中胰岛素、C肽测定在新生儿低血糖诊断中的临床意义。方法选取新生儿共325例,所有患者入院后立即取静脉血查胰岛素、C肽和血糖。结果低血糖组胰岛素、C肽明显高于正常血糖组,且胰岛素、C肽值越高,低血糖持续时间越长。结论胰岛素、C肽血清浓度对血糖的调节作用在新生儿期已经成熟,测定血清中胰岛素、C肽对预测低血糖持续时间具有重要指导意义。Objective To investigate the clinical significance of serum insulin and C‐peptide measurement in the diagnosis of neonatal hypoglycemia .Methods 325 newborns were randomly selected and taken venous blood for detecting insulin ,C‐peptide and glucose immediately after admission .Results The insulin and C‐peptide levels in the hypoglycemia group were significantly higher than those in the normal glucose group .Moreover the higher the C‐pep‐tide value was ,the longer the duration of hypoglycemia lasted .Conclusion The regulation role of serum insulin and C‐peptide concentrations is mature in the neonatal period .Detecting serum insulin and C‐peptide has an important guiding significance in predicting the persistent time of hypoglycemia .

关 键 词：胰岛素 C肽 新生儿低血糖 

分 类 号：R587.1[医药卫生—内分泌]