阴道超声结合血清β-hCG、孕酮测定对诊断早期输卵管妊娠的价值  

Value of transvaginal sonography combined with serum β-hCG and progesterone and in early diagnosis of ectopic pregnancy

作　　者：任翠云 李婉 

机构地区：[1]山东省鄄城县第二人民医院妇产科,山东鄄城274600

出　　处：《中国妇幼健康研究》2015年第2期381-382,共2页Chinese Journal of Woman and Child Health Research

摘　　要：目的：探讨阴道超声结合血清人绒膜促性腺激素（β-hCG）、孕酮检测在宫内妊娠与异位妊娠鉴别诊断中的价值，同时分析3种检测方法对诊断符合率的关系。方法根据妊娠结局将176例患者分为宫内正常妊娠组57例、宫内妊娠流产组34例、异位妊娠组85例，比较各组血清β-hCG、孕酮水平，并结合阴道超声进行分析。结果异位妊娠组的血清β-hCG值显著低于正常妊娠组（t＝4．887，P＜0．01），异位妊娠组和宫内妊娠流产组的血清β-hCG值差异无统计学意义（t＝0．866，P＞0．05）；异位妊娠组的孕酮水平显著低于正常妊娠组（t＝12．601，P＜0．01），异位妊娠组和流产组的孕酮水平差异无统计学意义（t＝0．610， P＞0．05）；异位妊娠组的子宫内膜厚度显著低于正常妊娠组和流产组（t值分别为14．740、2．732，均P＜0．05）。血清β-hCG、孕酮及阴道超声3者联合检测诊断异位妊娠符合率达94．9％，OR值是两者联合符合率的2-3倍，是单个诊断的3-7倍。结论阴道超声结合血清β-hCG、孕酮测定，可以极大地提高临床诊治早期异常妊娠疾病的准确率，对辅助诊断异位妊娠具有重要意义。Objective To analyze the value of serum β-hCG, progesterone and transvaginal sonography in early diagnosis of ectopic pregnancy and the coincidence rate of three methods.Methods According to pregnant outcomes 176 patients were divide into normal intrauterine pregnancy group （57 cases） , intrauterine pregnancy abortion group （34 cases） and ectopic pregnancy group （85 cases） .The serumβ-hCG and progesterone level were compared among different groups, and they were analyzed with vaginal ultrasound.Results The serumβ-HCG value in ectopic pregnancy group was lower than that of normal intrauterine pregnancy group （t=4.887,P〈0.01）, but there was no significant difference in serumβ-hCG level between ectopic pregnancy group and intrauterine pregnancy abortion group （ t=0.866, P〉0.05）.The progesterone level in ectopic pregnancy group was significantly lower than that in normal intrauterine pregnancy group （t=12.601, P 〈0.01）, but there was no significant difference in progesterone level between ectopic pregnancy group and intrauterine pregnancy abortion group （t=0.610,P〉0.05）.The endometrial thickness of ectopic pregnancy group was less than that of normal intrauterine pregnancy group and intrauterine pregnancy abortion group （ t value was 4.740 and 2.732, respectively, both P〈0.01）.The coincidence rate of serumβ-hCG and progesterone combined with transvaginal ultrasound in diagnosis of ectopic pregnancy was 94.9%, and the OR value was 2 -3 times of that by two of them and 3 -7 times of that by single detection.Conclusion Combined detection of serumβ-hCG and progesterone combined with transvaginal sonography can improve the accuracy in early diagnosis of ectopic pregnancy, and it is of great importance for auxiliary diagnosis.

关 键 词：异位妊娠 人绒膜促性腺激素 孕酮 阴道超声 二项分类Logistic回归 

分 类 号：R714.2[医药卫生—妇产科学]