HIV/AIDS病人服药依从性现状及影响因素分析  

Medication adherence and influence factors for taking medications among people living with HIV/AIDS

作　　者：陈艳霞[1] 刘钟应[2] 李星明[2] 袁晓青[1] 福燕[1] 高美霞[1] 孙盈红[1] 周梦戈 徐凤[2] 杨慧[2] 陈宇婧[2] 黄宇[2] 

机构地区：[1]首都医科大学附属北京佑安医院感染中心,北京100069 [2]首都医科大学卫生管理与教育学院,北京100069

出　　处：《中国艾滋病性病》2015年第4期268-272,共5页Chinese Journal of Aids & STD

摘　　要：目的了解艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人),对抗病毒治疗(ART)的依从性及其影响因素,为制定该人群健康管理的对策提供参考。方法选取2013年9-12月在北京市佑安医院参加爱心家园活动的HIV/AIDS病人,利用自行设计的问卷收集病人的相关信息,包括社会人口学信息、服药依从性信息、社会支持信息等。结果共计调查HIV/AIDS病人500例,有277例(55.40%)已经开始服用抗病毒药物,其中依从性好的215例(77.62%),依从性差的62例(22.38%)。影响依从性的主要因素为婚姻状况、户籍状况、经济状况、发病与感染状况和社会支持信息等;多因素分析中,服药时间、发病情况、社会支持利用度等因素对依从性的影响具有统计学意义(P<0.05)。结论抗病毒治疗中,影响HIV/AIDS病人的依从性因素是多方面的。应针对具体原因,提出改进的建议和措施。在临床工作中,应努力提高专业知识水平,加强沟通,增加社会支持力度和措施以增加依从性,改善艾滋病治疗和预防的效果。Objective The purpose of the study was to investigate the compliance status and influence factors in the human immunodefieieney virus/acquired immunodefieiency syndrome （HIV/AIDS） patients who are on anti-retrovirus therapy （ART） and provide scientific evidence for the health management of those patients. Methods A to- tal of 500 HIV/AIDS patients from the ＂Caring Home＂ of Beijing Youn Hospital were recruited in this study from September to December in 2013. Based on collecting their information of treatment and relevant information covering soeio-demography, drug compliance and social support was collected by questionnaires. Results Among the 500 participants, 277（55.40%）of them had begun antiretroviral therapy, the compliance of treatment was fine in 215 （77.62 % ）patients and 62 patients who has poor compliance accounted for 22.38 %. The main factors influencing the compliance included marital status, household registration status, economic status, the incidence and infection sta- tus. Multiple factors analysis showed that factors including administration time, disease status, support utilization affected compliance （P〈0.05）. Conclusion The factors that affect medication adherence of HIV/AIDS patients are many-sided. Therefore, we should provide improvement method and suggestion for every impact factor. In clinical work, we should improve the professional knowledge, enhance communication and increase social support and measures, in order to increase compliance according to the specific condition of each patient.

关 键 词：艾滋病病毒感染者/艾滋病人 抗病毒治疗 服药依从性 

分 类 号：R373.9[医药卫生—病原生物学] R512.91[医药卫生—基础医学]