轮状病毒胃肠炎患儿与非感染性腹泻患儿血清微量元素水平变化的病例对照研究  

Case- control study on the changes of serum trace elements among children with rotavirus gastroenteritis and children with non- infectious diarrhea

作　　者：王湘蓉[1] 刘嘉娜[1] 朱燕[1] 陈薇[1] 刘晓生[1] 

机构地区：[1]湖南省妇幼保健院儿科,湖南长沙410008

出　　处：《实用预防医学》2015年第6期669-671,共3页Practical Preventive Medicine

基　　金：湖南省科技厅一般项目(2011FJ4149)

摘　　要：目的通过对轮状病毒胃肠炎患儿及非感染性腹泻患儿锌、铁、铜、钙、镁及铅等微量元素水平的对照研究,了解轮状病毒感染对人体微量元素变化的影响。方法随机选取47名轮状病毒肠炎的患儿及56名非感染性腹泻的患儿分别测定研究对象的锌、铁、铜、钙、镁及铅等微量元素水平。结果轮状病毒胃肠炎患儿的锌、钙、镁这三种微量元素水平均低于非感染性腹泻患儿,轮状病毒患儿血铅水平则高于非感染性腹泻患儿,差异有统计学意义(P<0.05)。铜、铁元素含量差异无统计学意义(P>0.05)。结论轮状病毒肠炎患儿比非感染性腹泻患儿更易于发生微量元素失衡,在轮状病毒肠炎患儿的治疗过程中应该加强血清微量元素水平的监测。Objective To explore the impact of rotavims infection on the changes of serum trace elements, such as zinc, iron, copper, calcium, magnesium and lead through case- control study among children with rotavirus gastroenteritis and children with non - infectious diarrhea. Methods Forty- seven children with rotavirus gastroenteritis and 56 children with non - infectious diarrhea were randomly selected to serve as the research subjects, and the levels of serum zinc, iron, copper, calcium, magnesium and lead were determined. Results The levels of serum zinc, calcium and magnesium were significantly lower in children with rotavirus gastroenteriti8 than in children with non - infectious diarrhea （P 〈 0.05）, while the level of serum lead was signif- icantly higher （P 〈 0.05）. No statistically significant differences were found in the levels of serum copper and iron between the two groups （P 〉0.05）. Conclusions Children with rotavirus enteritis are more susceptible to suffering from trace element imbalance as compared with children with non - infectious diarrhea; and hence, monitoring of serum levels of trace elements should be intensified during the treatment of rotavirus enteritis.

关 键 词：轮状病毒胃肠炎 微量元素 儿童 病例对照研究 

分 类 号：R512.5[医药卫生—内科学]