绍兴市5个鸡场球虫分离株抗药性试验  

Drug resistance of Eimeria species isolated from five chicken farms in Shaoxing City

作　　者：蔡兰 朱顺海[2] 赵其平[2] 韩红玉[2] 黄兵[2] 董辉[2] 余招锋 鲍维琪 蒋位楚 

机构地区：[1]绍兴出入境检验检疫局,浙江绍兴312000 [2]中国农业科学院上海兽医研究所,农业部动物寄生虫学重点实验室,上海200241 [3]浙江出入境检验检疫局,浙江杭州310012 [4]绍兴市柯桥区畜牧兽医局,浙江绍兴312000

出　　处：《浙江农业学报》2015年第4期532-536,共5页Acta Agriculturae Zhejiangensis

基　　金：浙江检验检疫局科技计划项目(ZK201225)

摘　　要：为了解浙江绍兴地区规模化养鸡场防治球虫病的药物使用情况及鸡场球虫对常规药物的抗药性程度,对绍兴市5个县市规模化鸡场采集、分离、繁殖的球虫混合株进行抗马杜拉霉素和抗地克珠利的药物抗药性试验。试验设置了4个组:即感染给马杜拉霉素组、感染给地克珠利组、感染不给药组、健康组;以ACI,POAA,RLS,ROP这4项指标作为球虫抗药性的综合判定标准。结果显示,绍兴市随机抽取的5个规模化鸡场的球虫对这两种药物均产生了完全抗药性。说明绍兴市其余鸡场球虫可能也对马杜拉霉素和地克珠利产生了抗药性。因此,需要养殖户引起足够的重视,以免造成大的经济损失。Eimeria species were collected from five chicken farms in Shaoxing City,Zhejiang Province,and two anticoccidial drugs,i. e. Maduramicin and Diclazuril,were selected to test their drug resistance. The treatments were set as follows： Group 1 was infected with Eimeria oocysts and was medicated by Maduramicin; group 2 was infected with Eimeria oocysts and was medicated by Diclazuril; group 3 was infected with Eimeria oocysts yet was unmedicated; group 4 was uninfected and unmedicated. Drug resistance was assessed by ACI,POAA,RLS and ROP. The results revealed that all of the Eimeria species isolated were completely resistant to both Maduramicin and Diclazuril. It was suggested that the situation of drug resistance in chicken farms in Shaoxing City was serious. In order to avoid more economic loss,effective methods should be considered to control coccidiosis in this area.

关 键 词：球虫 马杜拉霉素 地克珠利 抗药性 

分 类 号：S852.72[农业科学—基础兽医学]