中国成年人受教育水平与代谢综合征发病风险的关系  

Relationship Between Educational Level and the Incidence of Metabolic Syndrome in Chinese Adults

作　　者：何宏海 陈纪春[1] 杨学礼[1] 黄建凤[1] 李莹[1] 李建新[1] 曹杰[1] 俞玲[2] 吴先萍[3] 陈娜萦 张荣敏 胡一河 李会仓 井斌 顾东风[1] 

机构地区：[1]北京协和医学院中国医学科学院国家心血管病中心阜外心血管病医院流行病学研究部,北京市100037 [2]福建省立医院 [3]四川省疾病预防控制中心慢病防治所 [4]广西省疾病预防控制中心 [5]南法信镇卫生院 [6]苏州市疾病预防控制中心 [7]宝鸡市中医医院 [8]山东省临朐县疾病预防控制中心

出　　处：《中国循环杂志》2015年第5期469-473,共5页Chinese Circulation Journal

基　　金：国家"十一五"科技支撑计划课题(2006BAI01A01);国家"十二五"科技支撑计划课题(2011BAI11B03和2011BAI09B03)

摘　　要：目的：研究中国成年人群受教育水平与代谢综合征（MS）发病风险之间的关系。方法：以中国心血管病流行病学多中心协作研究和中国心血管健康多中心合作研究为基线,于2007-2008年进行随访。调查人口学特征、社会经济状况、生活方式以及进行体格检查、实验室测定等,最终将12 784例35~74岁研究对象纳入分析。按照受教育水平将研究对象分成未上学、小学、初中、高中/中专和大专及以上5组,应用二分类logistic回归模型分析受教育水平与MS发病风险、基线吸烟和饮酒习惯之间的关系。结果：平均随访8.1年,2 760例发生MS。多因素调整后,与未上学者相比,小学、初中、高中/中专和大专及以上者的MS发病风险逐渐降低,RR（95%CI）分别为0.93（0.79~1.10）、0.97（0.81~1.16）、0.72（0.59~0.87）和0.57（0.45~0.72）,P趋势〈0.0001;大专及以上学历者有吸烟、嗜烟酒习惯的OR（95%CI）分别为0.25（0.19~0.34）和0.34（0.22~0.52）,有统计学意义。结论：中国成年人群中受教育程度低者的MS发病风险高,更有可能嗜烟酒,是心血管病的高危人群。Objective：To assess the relationship of educational level and the incidence of metabolic syndrome（MS） among Chinese adults aged 35~74 years in a prospective cohort study.Methods：At baseline,participants were investigated regarding demographic characteristics,socioeconomic status,lifestyle risk factors and other variables of MS in the China Multicenter Collaborative Study of Cardiovascular Epidemiology（1998） and China Cardiovascular Health Study（2000-2001）.The final analysis included 12 784 participants（6 179 men and 6 605 women） who were followed up in 2007-2008.Educational level was classified into 5 categories：illiteracy（n =1 241,9.71%）,primary（n =3 814,29.83%）,junior high（n =3 759,29.40%）,senior high（n =2 728,21.34%） and college or above（n =1 242,9.72%）.Binary logistic regression analyses were used to measure the association between educational level and the incidence of MS,as well as smoking and drinking.Results：A total of 2 760 incident MS were identified after an average of 8.1 years follow up.After adjustment for multi-variables,an inverse gradient in the incidence of MS was showed through categories of education.Compared with the illiteracy group,the RR（95% CI） of incident MS for persons with primary school,junior high,senior highand college or above education were 0.93（0.79~1.10）,0.97（0.81~1.16）,0.72（0.59~0.87） and 0.57（0.45~0.72）,respectively,（P for trend〈0.0001）.Persons in college or above education status were less likely smoking（OR=0.25,95% CI：0.19~0.34） or tobacco and alcohol addiction（OR=0.34,95% CI：0.22~0.52）,P 〈0.05.Conclusion：Lower education is associated with higher risk of incident MS in Chinese adults.Lower educated persons are more likely addicted to tobacco and alcohol,which might partially explain the susceptibility of metabolic syndrome among adults with lower education.

关 键 词：受教育水平 代谢综合征 发病率 队列研究 

分 类 号：R54[医药卫生—心血管疾病]