降压治疗对脑卒中再发预防的研究——PROGRESS和PATS试验及其临床意义  

Antihypertensive Therapy Research on the Prevention of Stroke Recurrence——PROGRESS and PATS test and Its clinical Significance

作　　者：林莉 郑彩娇 

机构地区：[1]临海市杜桥中心卫生院,浙江临海317016

出　　处：《中国初级卫生保健》2015年第5期128-129,共2页Chinese Primary Health Care

摘　　要：前瞻性临床研究显示,患者首次脑卒中的发病率同患有心肌梗死、非脑卒中患者的血压有直接的关系,而经抗高血压临床治疗对照试验,可知舒张压的下降同高血压患者脑卒中再发的几率呈线性关系,平均每降低5~6 mm Hg,发病几率则减少30%~40%。针对高血压人群及非高血压人群进行降压治疗,可以有效预防脑卒中再发,可以通过临床PROGRESS、PATS试验进行验证。通过研究降压治疗对脑卒中再发预防的研究,分析PROGRESS和PATS试验及其临床意义,以期通过降压治疗的方式,控制脑卒中的发病率,改善脑血管疾病患者的生活质量,更好的指导临床治疗。A prospective clinical study showed that patients with the first onset of stroke rates with myocardial infarction, non-stroke patient＇s blood pressure has a direct relationship, and by the anti-hypertensive therapy clinical trials, it conlol see the same decline in diastolic blood pressure chance of recurrence in patients with stroke showed a linear relationship between the average per reduce 5-6mmHg, risk of disease is reduced by 30%~40%. Conducted for hypertension and non-hypertensive patients antihypertensive treatment, can effectively prevent stroke recurrence, through clinical PROGRESS, PATS test for verification. Through the study of antihypertensive therapy on stroke recurrence prevention study, analyze and PATS PROGRESS trial and its clinical significance in order by way of antihypertensive therapy to control the incidence of stroke, improve the quality of life in patients with cerebrovascu- lar disease and more good clinical treatment.

关 键 词：降压治疗 脑卒中再发 PROGRES试验 PATS试验 

分 类 号：R34[医药卫生—基础医学]