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出 处:《中国性科学》2015年第5期3-5,共3页Chinese Journal of Human Sexuality
基 金:浙江省温岭市科技计划项目(2013ZHB004)
摘 要:目的:观察保留性功能全膀胱切除回肠原位新膀胱术与全膀胱切除回肠原位新膀胱术对术后性功能、控尿功能和肿瘤控制的影响。方法:临床纳入浸润性膀胱癌患者50例,根据入院后手术方案的不同分为研究组与对照组。研究组进行保留性功能全膀胱切除回肠原位新膀胱术,对照组进行全膀胱切除回肠原位新膀胱术。观察勃起功能指数、每周性交次数、近期和远期排尿情况以及术后肿瘤复发及死亡率等。结果:研究组治疗后勃起功能指数为(22.1±5.6)分,对照组为(18.3±4.1)分,差异无显著性(P>0.05);研究组近期排尿异常率、远期排尿异常率分别为16%、0%,对照组近期排尿异常率、远期排尿异常率分别为44%、20%,差异均有显著性(P<0.05);研究组患者1年、3年生存率分别为96%、72%,对照组患者分别为76%、44%,差异显著(P<0.05)。结论:保留性功能全膀胱切除回肠原位新膀胱术治疗浸润性膀胱癌,能够有效改善患者的术后性功能,增强患者的控尿功能。此外,对患者1年、3年生存率有明显提高,值得推广。Objectives:To observe the effect of sexual function preserved radical cystectomy and ileal neo-bladder on postoperative sexual function,urinary function and tumor control.Methods:50 patients with invasive bladder cancer in our hospital were selected,and divided into the study group and control group according to differ-ent operation scheme after admission.The study group received sexual functional preserved radical cystectomy and ileal neobladder,and the control group was given cystectomy and ileal neobladder.Index of erectile function,week-ly frequency of sexual intercourse,the short -term and long -term voiding and postoperative tumor recurrence and mortality were observed.Results:Erectile function index of the study group and control group after treatment was (22.1 ±5.6)and (18.3 ±4.1)respectively,with no significant difference (P 〉0.05).The urinary abnormality rate and abnormal rate of long -term voiding in the study group were respectively 16% and 0%,and the recently micturition abnormal rate and long -term urinary abnormality rate in control group were respectively 44% and 20%, with significant difference (P 〈0.05).The 1 -year and 3 -year survival rates of the study group were 96% and 72%,while those of the control group were 76% and 44%,with no significant difference (P 〉0.05).Conclu-sion:The sexual function preserved cystectomy and ileal neobladder can effectively improve the postoperative sexual function of patients and enhance the patient's urinary continence,with a high 1 -year and 3 -year survival rate, thusly worthy of promotion.
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