白色念珠菌检测在龟头炎诊断中的临床应用效果分析  

Clinical application of Candida albicans detection in the diagnosis of balanitis

作　　者：吴利军 蔡光辉[2] 

机构地区：[1]大冶市人民医院检验科,湖北黄石435100 [2]黄石市中心医院皮肤科,湖北黄石435000

出　　处：《中国性科学》2015年第5期15-17,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探析白色念珠菌检测对龟头炎的诊疗过程的指导作用。方法:回顾性分析我院门诊2012年1月至2014年3月期间收治的118例龟头炎患者的临床资料,真菌镜检均为阳性,行菌株培养和鉴定以及体外药敏试验,分析菌株检出率、病原菌分布情况以及药敏试验结果。结果:118例患者真菌镜检均为阳性,念珠菌阳性率为94.92%;白色念珠菌106株(94.64%)。培养菌株对制霉菌素和克霉唑敏感率100.00%;白色念珠菌对氟康唑、伊曲康唑敏感性分别为56.86%、60.78%;1株近平滑念珠菌对咪康唑中度敏感,对其他药物均敏感;光滑念珠菌对所有药物均敏感;克柔念珠菌对咪康唑耐药,其余药物均敏感。结论:白色念珠菌仍为真菌性龟头炎主要病原菌,其确诊依赖于真菌镜检和菌种培养鉴定,体外药敏试验为临床用药提供重要的参考依据,有利于彻底根治龟头炎,提高临床治疗效果,进而促进患者生活质量的改善。Objectives：To explore the guiding role of Candida albicans on diagnosis and treatment of balan-itis.Methods：The clinical data of 118 balanitis patients treated in our hospital from 2012 January to 2014 March were retrospectively analyzed.The microscopic fungi were positive;the bacteria culture and identification and drug sensitivity test in vitro,analysis of strain rate,pathogenic bacteria distribution and drug susceptibility test were con-ducted.Results：118 patients were positive in microscopic fungi test,an positive rate of 94.92%;106 were Candi-da albicans （94.64%）;sensitive rate of culture strains against nystatin and clotrimazole was 100%;the suscepti-bility of Candida albicans to fluconazole and itraconazole were 56.86% and 60.78% respectively;1 strain of candi-da parapsilosis was moderately sensitive against miconazole,and sensitive to the other agents;Candida glabrata were susceptible to all drugs;Candida krusei was resistant to miconazole,and sensitive to the rest of the drugs.Conclu-sion：Candida albicans is the major pathogenic fungus of balanitis,whose diagnosis is dependent on the microscopic examination of fungal and bacterial culture and identification.The drug sensitivity test in vitro provides reference for clinical medication,to eradicate the balanitis,improve the clinical treatment effect,and promote the improvement in life quality of patients.

关 键 词：龟头炎 白色念珠菌 诊断 治疗 应用价值 

分 类 号：R697.1[医药卫生—泌尿科学]