早发型先天性梅毒患儿的影像学特征分析及对临床治疗效果的影响  

Radiological features and clinical treatment of early- onset congenital syphilis

作　　者：黄昊[1] 马俊如[2] 陆茂[3] 

机构地区：[1]成都医学院第一附属医院放射科,成都610500 [2]成都医学院第一附属医院妇产科,成都610500 [3]成都医学院第一附属医院皮肤科,成都610500

出　　处：《中国性科学》2015年第5期47-49,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨分析早发型先天性梅毒患儿的影像学的临床特征及临床治疗方法。方法:回顾性分析2010年3月至2013年期间我院收治的60例早发型先天性梅毒患儿的骨骼X线片和临床资料,分析其X线的临床表现;所有患者给予常规水剂青霉素治疗2个疗程,观察患者的临床疗效。结果:经过X线影像检查,40例患儿出现骨骼改变:其中36例表现为股骨、胫腓骨、肱骨或尺桡骨出现临时钙化带增宽或其下方出现透亮带的现象,其他骨骼如跟骨、距骨、肩胛骨也出现受累状况;35例出现骨骼反应,以胫骨、股骨、尺骨、腓骨多见,奇特骨骼也存在这一状况;22例患儿出现骨质损坏,以股骨、胫骨、肱骨、尺骨多见,其他骨骼如锁骨也出现这一状况;经过临床治愈,60例患儿的临床治疗总有效率为86.7%。结论:早期先天性梅毒患儿的骨骼会发生改变,有一定的影像学特征,这可以辅助临床诊断早发型先天性骨梅毒,评估骨损害的程度;经过青霉素及时治疗,可治疗早期先天性梅毒患儿,获得较好的临床疗效。Objectives：To investigate the radiographic characteristics and clinical treatment of early -onset congenital syphilis.Methods：A retrospective analysis on the X -ray and clinical data of 60 patients with early -onset congenital syphilis in our hospital from March 2010 to 2013 was conducted.All patients received conventional aqueous penicillin for two courses of treatment,to observe the clinical efficacy.Results：Through X -ray imaging, 40 cases were found have bone changes：for example,the femur,tibia and fibula,humerus or ulna appear below the provisional calcification or radiolucent band broadening phenomenon,other bones such as the calcaneus,talus, scapula also appeared involvement situation;35 cases had bone reactions,mainly in tibia,femur,ulna,fibula com-mon,including peculiar bones;22 cases were found bone damage to the femur,tibia,humerus,ulna common,oth-er bones such as the clavicle also appeared in this situation;after clinical treatment,the total effective rate of the 60 cases was 86.7%.Conclusion：The bone of children with congenital syphilis will change,with certain imaging fea-tures,which is conducive for early clinical diagnosis of congenital bone syphilis,assessment the extent of early -on-set congenital bone damage.Timely treatment with penicillin can cure early congenital syphilis,with good clinical efficacy.

关 键 词：早发型先天性梅毒 影像学特征 临床疗效 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]