日粮中添加(-)-羟基柠檬酸对肉鸡脂肪代谢的影响  

Effects of(- )- hydroxycitric acid on lipid metabolism in broiler chickens

作　　者：韩婧[1] 马海田[1] 

机构地区：[1]南京农业大学动物生物化学研究室,江苏南京210095

出　　处：《畜牧与兽医》2015年第5期20-25,共6页Animal Husbandry & Veterinary Medicine

基　　金：教育部新世纪优秀人才项目(NCE-10-0495)

摘　　要：为探讨(-)-羟基柠檬酸[(-)-HCA]对肉鸡脂肪代谢的影响,120羽21日龄罗氏308肉鸡随机分成4组,每组3个重复,每个重复10羽。分别于基础日粮中添加0、150、300和600 mg/kg的(-)-HCA,饲喂至50日龄,各组分别从每个重复中随机抽取4只肉鸡宰杀,采集血液、肝脏、腹脂、肌肉等样品。试验结果表明,与对照组相比,3个剂量组的(-)-HCA对腹脂率、日采食量、料重比影响虽无统计学上的差异,但3个剂量(-)-HCA的处理均有降低使腹脂率、日采食量,并提高饲料转化率的趋势。与对照组相比,600 mg/kg的(-)-HCA处理能显著降低肉鸡血清中甘油三酯(TG)和总胆固醇(TC)的含量(P<0.05),但3个剂量组的(-)-HCA均可显著降低血清中游离脂肪酸(NEFA)的含量显著(P<0.05)。与对照组相比,300和600 mg/kg的(-)-HCA处理可显著升高血清中高密度脂蛋白-胆固醇(HDL-C)的含量(P<0.05),3个剂量的(-)-HCA处理均可显著降低血清中低密度脂蛋白-胆固醇(LDL-C)的含量(P<0.05)。与对照组相比,300 mg/kg的(-)-HCA处理可显著提高肉鸡肝糖元的含量(P<0.05),但3个剂量组的(-)-HCA对肌糖元的含量均无显著影响(P>0.05)。3个剂量的(-)-HCA处理对肝脂酶活性均无统计学上的差异(P>0.05),但不同剂量的(-)-HCA处理均有提高肝脂酶活性的趋势。提示(-)-HCA可通过抑制脂肪酸的合成、加快脂肪的分解,从而减少脂肪在肉鸡体内的沉积。To assess the effects of hydroxycitric acid （（-） -HCA） on lipid metabolism in broiler chickens, a total of 120 21-day-old birds were randomly allocated to four groups, with each group replicated three times and each replicate involving 30 birds. The broilers were provided with a commercial diet supplement of （-） -HCA at 0, 150, 300, 600mg/kg of the diet, respectively, for a period of 4 weeks ad libitum. Three broilers per replicate from each treatment were chosen randomly and slaughtered to collect specimens of blood, liver, abdomi- nal fat at 50 days old. The results showed that compared with the control group, although there were no statistical difference in the percentage of abdominal fat weight, daily intake and feed intake/daily gain in three levels of （-） -HCA groups, but the addition of （-） -HCA de- creased the daily feed intake and increased feed intake/daily gain. Compared with the control group, 600mg/kg （-） -HCA could signifi- cantly decrease the content of TG and TC （P〈0. 05 ） in serum, while three levels of （-） -HCA could significantly decrease the content of NEFA in serum （P〈0. 05 ）. Compared with the control group, （-） -HCA treatment of 300 and 600mg/kg significantly increased the con- tent of HDL-C in serum （P〈0. 05 ）, and three levels of （-） -HCA treatment could significantly decrease the content of LDL-C （P〈0. 05 ） in serum. Compared with the control group, the 300mg/kg of （-） -HCA treatment significantly increased glycogen content in the livers of broilers （P〈0.05） , while the three levels of （-） -HCA had no significant effects on glycogen in muscle tissue （P〉0. 05 ）. The hepatic li- pase activities were not statistically different among three levels of （-） -HCA treatment （P〉0.05）, but there was an increasing trend. It suggests that （-） -HCA could decrease fat accumulation in broilers by the inhibition of fatty acid synthesis and acceleration of fat metabolism.

关 键 词：(-)-羟基柠檬酸 肉鸡 脂肪代谢 

分 类 号：S831.5[农业科学—畜牧学]