ABI与CAVI评价原发性高血压患者血压控制不良对动脉硬化影响的研究  

ABI and CAVI in assessment of arteriosclerosis progress in primary hypertensive patients with poor blood pressure control

作　　者：朱利月[1] 任爱华[1] 俞志红[1] 寿晓玲[1] 王雁 刘新文[1] 

机构地区：[1]浙江医院康复治疗中心,杭州310013

出　　处：《浙江医学》2015年第7期572-575,共4页Zhejiang Medical Journal

基　　金：浙江省医药卫生一般研究计划(2012KYA001);浙江省医药卫生一般研究计划(2014KYB015);浙江省医药卫生科技计划项目(2012KYA010)

摘　　要：目的探讨踝-臂指数(ABI)与心踝指数(CAVI)评价原发性高血压患者血压控制不良对动脉硬化影响的临床应用价值。方法原发性高血压患者105例,根据24h动态血压结果,分为高血压控制达标组46例和高血压控制不良组59例,另择同期行健康体检者41例为正常对照组,分别测定3组的CAVI、ABI、BMI值并进行两两比较。结果 3组比较结果显示:CAVI、ABI、BMI值差异均有统计学意义(均P<0.05);其中血压控制不良组双侧CAVI值明显增高,双侧ABI值明显降低,BMI值增高,差异均有统计学意义(均P<0.05);而高血压控制达标组与正常对照组比较双侧CAVI、双侧ABI、BMI值差异均无统计学意义(均P>0.05)。结论血压控制不良将促进动脉硬化进展,应用ABI与CAVI值可准确评价高血压控制不良对动脉弹性的影响。Objective The evaluate the application of ankle-brachial index （ABI） and cardio-ankle vascular index （CAVI） in assessment of arteriosclerosis progress in primary hypertensive patients with poor blood pressure control. Methods One hun- dred and five patients with primary hypertension were enrolled in the study, including 46 cases with well blood pressure control and 59 cases with poor blood pressure control; 41 healthy subjects served as controls. The CAVI, ABI and BMI were determined and compared among 3 groups. Results Compared to well-control group the bilateral CAVl and BMI in poor-control group were significantly increased and ABI was significantly decreased （all P〈0.05）. There were no significant differences in bilateral CAVI, bilateral ABI and BMI values between well-control group and healthy controls （P 〉0.05）. Conclusion The ABI and CAVl values can accurately evaluate the adverse effect of poor blood pressure control on arterial elasticity in primary hypertensive patients.

关 键 词：原发性高血压 血压控制不良 动脉硬化 

分 类 号：R544.1[医药卫生—心血管疾病]